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	<title>ABCA7 - Revision history</title>
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	<updated>2026-04-22T23:47:45Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=ABCA7&amp;diff=6496778&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=ABCA7&amp;diff=6496778&amp;oldid=prev"/>
		<updated>2025-03-17T03:05:50Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 03:05, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=ABCA7&amp;diff=6202364&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=ABCA7&amp;diff=6202364&amp;oldid=prev"/>
		<updated>2025-02-10T04:52:54Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 04:52, 10 February 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=ABCA7&amp;diff=5377697&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=ABCA7&amp;diff=5377697&amp;oldid=prev"/>
		<updated>2024-03-09T20:57:58Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;ABCA7&amp;#039;&amp;#039;&amp;#039; is a gene that in humans is encoded by the ABCA7 protein. It is a member of the [[ATP-binding cassette transporter]]s, a large family of proteins that transport various molecules across the extra- and intra-cellular membranes. ABCA7 has been implicated in the pathogenesis of [[Alzheimer&amp;#039;s disease]], and genetic variations in the ABCA7 gene have been associated with an increased risk of late-onset Alzheimer&amp;#039;s disease.&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
The ABCA7 protein is a member of the [[ABC transporter]]s, which utilize the energy of ATP hydrolysis to carry out certain biological processes, including transmembrane transport of various molecules. ABCA7 is highly expressed in the brain and is involved in the regulation of [[lipid metabolism]], including the transport of [[cholesterol]] and [[phospholipids]].&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
Several studies have identified a link between genetic variations in the ABCA7 gene and an increased risk of late-onset Alzheimer&amp;#039;s disease. The exact mechanism by which ABCA7 contributes to Alzheimer&amp;#039;s disease is not fully understood, but it is thought to be related to its role in lipid metabolism and the regulation of [[amyloid-beta]] production.&lt;br /&gt;
&lt;br /&gt;
== Research ==&lt;br /&gt;
Research into the role of ABCA7 in Alzheimer&amp;#039;s disease is ongoing. Understanding the function of ABCA7 and its role in disease pathogenesis may lead to the development of new therapeutic strategies for Alzheimer&amp;#039;s disease.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[ATP-binding cassette transporter]]&lt;br /&gt;
* [[Alzheimer&amp;#039;s disease]]&lt;br /&gt;
* [[Lipid metabolism]]&lt;br /&gt;
* [[Amyloid-beta]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
[[Category:Alzheimer&amp;#039;s disease]]&lt;br /&gt;
[[Category:ATP-binding cassette transporters]]&lt;br /&gt;
&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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