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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=ABCA2</id>
	<title>ABCA2 - Revision history</title>
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	<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ABCA2&amp;action=history"/>
	<updated>2026-05-11T13:12:41Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=ABCA2&amp;diff=6496482&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ABCA2&amp;diff=6496482&amp;oldid=prev"/>
		<updated>2025-03-17T02:53:58Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 02:53, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l25&quot;&gt;Line 25:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=ABCA2&amp;diff=6202200&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ABCA2&amp;diff=6202200&amp;oldid=prev"/>
		<updated>2025-02-10T04:49:10Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 04:49, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l24&quot;&gt;Line 24:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{medicine-stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=ABCA2&amp;diff=5378548&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=ABCA2&amp;diff=5378548&amp;oldid=prev"/>
		<updated>2024-03-09T22:00:13Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;ABCA2&amp;#039;&amp;#039;&amp;#039;, also known as &amp;#039;&amp;#039;&amp;#039;ATP-binding cassette sub-family A member 2&amp;#039;&amp;#039;&amp;#039;, is a protein that in humans is encoded by the ABCA2 gene. It is a member of the [[ATP-binding cassette transporter]]s, a large family of proteins that transport various molecules across the extra- and intra-cellular membranes.&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
ABCA2 is a member of the superfamily of [[ATP-binding cassette (ABC) transporter]]s. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transport function of ABCA2 is not yet clearly defined, but it is thought to play a role in [[lipid homeostasis]] and the regulation of [[cholesterol]].&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
Mutations in the ABCA2 gene have been associated with a number of diseases, including [[Alzheimer&amp;#039;s disease]], [[Parkinson&amp;#039;s disease]], and [[cancer]]. In Alzheimer&amp;#039;s disease, ABCA2 is thought to play a role in the accumulation of [[amyloid beta]] in the brain, a key event in the pathogenesis of the disease. In cancer, overexpression of ABCA2 has been observed in several types of tumors, suggesting a role in tumor progression.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[ATP-binding cassette transporter]]&lt;br /&gt;
* [[Alzheimer&amp;#039;s disease]]&lt;br /&gt;
* [[Parkinson&amp;#039;s disease]]&lt;br /&gt;
* [[Cancer]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/20 NCBI Gene]&lt;br /&gt;
* [https://www.uniprot.org/uniprot/Q9BZC7 UniProt]&lt;br /&gt;
&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:ATP-binding cassette transporters]]&lt;br /&gt;
[[Category:Genes on human chromosome 9]]&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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