Prab: CSV import

2025-02-15T11:00:06Z

CSV import

← Older revision		Revision as of 11:00, 15 February 2025
Line 1:		Line 1:
	~~{{Short description\|Synthetic cannabinoid}}~~		== 5F-EMB-PINACA ==
	~~{{Drugbox~~
	~~\| verifiedfields~~ = ~~changed~~
	~~\| verifiedrevid~~ = ~~477002123~~
	~~\| IUPAC_name = (S)-N-(1-amino-3-methyl-1-oxobutan-2~~-~~yl)~~-~~1-(5-fluoropentyl)-1H-indazole-3-carboxamide~~
	~~\| image~~ = ~~5F-AEB_structure.png~~
	~~\| width~~ = ~~200~~
	}}

	~~'''~~5F-~~EMB-PINACA''' is a synthetic cannabinoid that has been used in scientific research and is a potent agonist~~ of ~~the [[cannabinoid receptor]]s. It is structurally related to other synthetic cannabinoids such as [[AB-PINACA]] and [[~~5F-AB-PINACA]].		[[File:5F-AEB_structure.png\|thumb\|right\|Chemical structure of 5F-EMB-PINACA]]

	~~==Chemical structure==~~		'''5F-EMB-PINACA''' is a synthetic cannabinoid that has been used in scientific research and is often found in synthetic cannabis products. It is a potent agonist of the [[cannabinoid receptor]]s, which are part of the [[endocannabinoid system]] in the human body.
	5F-EMB-PINACA is ~~classified as an indazole-based~~ synthetic cannabinoid~~. Its chemical structure includes a 5-fluoropentyl chain attached to the indazole core, which~~ is ~~a common feature~~ in ~~many~~ synthetic ~~cannabinoids~~. ~~The compound also contains an amide linkage to~~ a ~~valine methyl ester moiety~~, which ~~contributes to its binding affinity and potency at~~ the ~~cannabinoid receptors~~.

	==~~Pharmacology~~==		=== Chemical Structure ===
	5F-EMB-PINACA ~~acts as a full agonist at the [[CB1 receptor\|CB<sub>1</sub>]]~~ and ~~[[CB2 receptor\|CB<sub>2</sub>]] receptors, which are part of the [[endocannabinoid system]]. This system~~ is ~~involved in regulating various physiological processes including mood, memory, and pain sensation~~. The ~~activation~~ of ~~these receptors by~~ 5F-EMB-PINACA ~~can lead~~ to ~~psychoactive effects similar to those produced by [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]]~~.		5F-EMB-PINACA is chemically related to other synthetic cannabinoids and is characterized by its indazole-based structure. The chemical structure of 5F-EMB-PINACA includes a fluorine atom, which is a common feature in many synthetic cannabinoids to enhance their potency and metabolic stability.

	==~~Legal status~~==		=== Pharmacology ===
	~~Due to its potential for abuse and lack of medical use,~~ 5F-EMB-PINACA ~~has been classified~~ as a ~~controlled substance~~ in ~~several countries~~. ~~It is often included~~ in ~~the category~~ of ~~"new~~ psychoactive ~~substances"~~ (~~NPS~~), ~~which are synthetic drugs designed to mimic~~ the ~~effects~~ of ~~traditional illicit drugs~~.		5F-EMB-PINACA acts as a full agonist at the [[CB1 receptor]] and [[CB2 receptor]], which are the primary receptors for cannabinoids in the body. These receptors are involved in a variety of physiological processes including pain sensation, mood, and memory. The activation of these receptors by 5F-EMB-PINACA can lead to psychoactive effects similar to those of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]].

	==~~Health effects~~==		=== Effects and Toxicity ===
	The ~~use~~ of 5F-EMB-PINACA ~~has been associated with~~ adverse ~~health~~ effects~~, including~~ [[tachycardia]], [[hypertension]], [[nausea]], and [[~~hallucinations~~]]. In ~~severe~~ cases, it can ~~lead to~~ [[~~acute kidney injury~~]] ~~and~~ [[~~seizures~~]]~~. The variability in potency and purity of synthetic cannabinoids like 5F-EMB-PINACA increases the risk of overdose and other harmful effects~~.		The effects of 5F-EMB-PINACA can include euphoria, relaxation, altered perception, and in some cases, anxiety or paranoia. Due to its high potency, there is a significant risk of overdose, which can lead to severe adverse effects such as [[tachycardia]], [[hypertension]], [[nausea]], and [[vomiting]]. In some cases, severe toxicity can result in [[seizures]], [[coma]], or even death.

	==~~Synthesis~~==		=== Legal Status ===
	The ~~synthesis~~ of 5F-EMB-PINACA ~~involves the reaction of an indazole core with~~ a ~~fluorinated alkyl chain~~ and ~~an amino acid derivative~~. ~~The process requires careful control of reaction conditions~~ to ~~ensure the correct stereochemistry~~ and ~~purity of the final product~~.		The legal status of 5F-EMB-PINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies often place synthetic cannabinoids like 5F-EMB-PINACA under temporary bans while further research is conducted to assess their safety and potential for harm.

	==Related ~~pages~~==		=== Synthesis ===
			The synthesis of 5F-EMB-PINACA involves the reaction of an indazole core with various chemical reagents to introduce the fluorine atom and other functional groups. The process requires specialized knowledge in organic chemistry and access to controlled laboratory environments.

			== Related Pages ==
	* [[Synthetic cannabinoids]]		* [[Synthetic cannabinoids]]
	* [[Cannabinoid receptor]]		* [[Cannabinoid receptor]]
	* [[Endocannabinoid system]]		* [[Endocannabinoid system]]
	* [[~~New psychoactive substances~~]]		* [[Tetrahydrocannabinol]]

	~~==Gallery==~~
	~~<gallery>~~
	~~5F-AEB_structure.png\|Chemical structure of 5F-EMB-PINACA~~
	~~</gallery>~~

	[[Category:Synthetic cannabinoids]]		[[Category:Synthetic cannabinoids]]
	~~[[Category:Designer drugs]]~~

Prab: CSV import

2025-02-11T21:29:02Z

CSV import

New page

{{Short description|Synthetic cannabinoid}}
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477002123
| IUPAC_name = (S)-N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide
| image = 5F-AEB_structure.png
| width = 200
}}

'''5F-EMB-PINACA''' is a synthetic cannabinoid that has been used in scientific research and is a potent agonist of the [[cannabinoid receptor]]s. It is structurally related to other synthetic cannabinoids such as [[AB-PINACA]] and [[5F-AB-PINACA]].

==Chemical structure==
5F-EMB-PINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes a 5-fluoropentyl chain attached to the indazole core, which is a common feature in many synthetic cannabinoids. The compound also contains an amide linkage to a valine methyl ester moiety, which contributes to its binding affinity and potency at the cannabinoid receptors.

==Pharmacology==
5F-EMB-PINACA acts as a full agonist at the [[CB1 receptor|CB<sub>1</sub>]] and [[CB2 receptor|CB<sub>2</sub>]] receptors, which are part of the [[endocannabinoid system]]. This system is involved in regulating various physiological processes including mood, memory, and pain sensation. The activation of these receptors by 5F-EMB-PINACA can lead to psychoactive effects similar to those produced by [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]].

==Legal status==
Due to its potential for abuse and lack of medical use, 5F-EMB-PINACA has been classified as a controlled substance in several countries. It is often included in the category of "new psychoactive substances" (NPS), which are synthetic drugs designed to mimic the effects of traditional illicit drugs.

==Health effects==
The use of 5F-EMB-PINACA has been associated with adverse health effects, including [[tachycardia]], [[hypertension]], [[nausea]], and [[hallucinations]]. In severe cases, it can lead to [[acute kidney injury]] and [[seizures]]. The variability in potency and purity of synthetic cannabinoids like 5F-EMB-PINACA increases the risk of overdose and other harmful effects.

==Synthesis==
The synthesis of 5F-EMB-PINACA involves the reaction of an indazole core with a fluorinated alkyl chain and an amino acid derivative. The process requires careful control of reaction conditions to ensure the correct stereochemistry and purity of the final product.

==Related pages==
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Endocannabinoid system]]
* [[New psychoactive substances]]

==Gallery==
<gallery>
5F-AEB_structure.png|Chemical structure of 5F-EMB-PINACA
</gallery>

[[Category:Synthetic cannabinoids]]
[[Category:Designer drugs]]

5F-EMB-PINACA - Revision history

Prab: CSV import

Prab: CSV import