https://wikimd.com/index.php?action=history&feed=atom&title=3-Methyl-PCPy 2026-04-07T04:36:05Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=3-Methyl-PCPy&diff=6294428&oldid=prev 2025-02-15T11:06:52Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:06, 15 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l3">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File:3-Me-PCPy_Structure.svg|thumb|right|Chemical structure of 3-Methyl-PCPy]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File:3-Me-PCPy_Structure.svg|thumb|right|Chemical structure of 3-Methyl-PCPy]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''3-Methyl-PCPy''' is a chemical compound that belongs to the class of [[arylcyclohexylamines]]. It is a derivative of [[<del style="font-weight: bold; text-decoration: none;">PCPy</del>]], which is <del style="font-weight: bold; text-decoration: none;">a </del>[[dissociative anesthetic]] <del style="font-weight: bold; text-decoration: none;">similar </del>to <del style="font-weight: bold; text-decoration: none;">[[phencyclidine]] (</del>PCP<del style="font-weight: bold; text-decoration: none;">). The compound is known for its [[NMDA receptor]] antagonistic properties</del>, which <del style="font-weight: bold; text-decoration: none;">contribute to </del>its <del style="font-weight: bold; text-decoration: none;">psychoactive </del>effects.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''3-Methyl-PCPy''' is a chemical compound that belongs to the class of [[arylcyclohexylamines]]. It is a derivative of [[<ins style="font-weight: bold; text-decoration: none;">PCP (phencyclidine)</ins>]], which is <ins style="font-weight: bold; text-decoration: none;">known for its </ins>[[dissociative anesthetic]] <ins style="font-weight: bold; text-decoration: none;">properties. The addition of a methyl group </ins>to <ins style="font-weight: bold; text-decoration: none;">the </ins>PCP <ins style="font-weight: bold; text-decoration: none;">structure results in 3-Methyl-PCPy</ins>, which <ins style="font-weight: bold; text-decoration: none;">has been studied for </ins>its <ins style="font-weight: bold; text-decoration: none;">pharmacological </ins>effects <ins style="font-weight: bold; text-decoration: none;">and potential applications in neuroscience research</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== Chemical Structure ==</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== Chemical Structure <ins style="font-weight: bold; text-decoration: none;">and Properties </ins>==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>3-Methyl-PCPy is <del style="font-weight: bold; text-decoration: none;">structurally related </del>to <del style="font-weight: bold; text-decoration: none;">PCPy</del>, with the addition of a methyl group at the <del style="font-weight: bold; text-decoration: none;">third </del>position of the <del style="font-weight: bold; text-decoration: none;">[[phenyl </del>ring<del style="font-weight: bold; text-decoration: none;">]]</del>. This modification <del style="font-weight: bold; text-decoration: none;">alters its pharmacological profile, potentially affecting its potency </del>and <del style="font-weight: bold; text-decoration: none;">duration of action. The chemical structure of 3-Methyl-PCPy is depicted in the image provided</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>3-Methyl-PCPy is <ins style="font-weight: bold; text-decoration: none;">characterized by the presence of a cyclohexylamine core with an aryl group attached. The chemical structure is similar </ins>to <ins style="font-weight: bold; text-decoration: none;">that of PCP</ins>, with <ins style="font-weight: bold; text-decoration: none;">the key difference being </ins>the addition of a methyl group at the <ins style="font-weight: bold; text-decoration: none;">3-</ins>position of the <ins style="font-weight: bold; text-decoration: none;">cyclohexyl </ins>ring. This modification <ins style="font-weight: bold; text-decoration: none;">can influence the compound's binding affinity </ins>and <ins style="font-weight: bold; text-decoration: none;">activity at various [[neurotransmitter receptors]]</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Pharmacology ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Pharmacology ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>3-Methyl-PCPy acts primarily as an [[NMDA receptor antagonist]]<del style="font-weight: bold; text-decoration: none;">. The NMDA receptor is a subtype of [[glutamate receptor]] that plays a crucial role </del>in <del style="font-weight: bold; text-decoration: none;">[[synaptic plasticity]] and [[memory function]]</del>. By <del style="font-weight: bold; text-decoration: none;">inhibiting this </del>receptor, <del style="font-weight: bold; text-decoration: none;">3-Methyl-PCPy </del>can <del style="font-weight: bold; text-decoration: none;">induce [[</del>dissociative<del style="font-weight: bold; text-decoration: none;">]] and [[hallucinogenic]] </del>effects. <del style="font-weight: bold; text-decoration: none;">These effects are similar to those produced by </del>other <del style="font-weight: bold; text-decoration: none;">arylcyclohexylamines, </del>such as [[ketamine]] and <del style="font-weight: bold; text-decoration: none;">PCP</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>3-Methyl-PCPy acts primarily as an [[NMDA receptor antagonist]]<ins style="font-weight: bold; text-decoration: none;">, similar to other compounds </ins>in <ins style="font-weight: bold; text-decoration: none;">the arylcyclohexylamine class</ins>. By <ins style="font-weight: bold; text-decoration: none;">blocking the NMDA </ins>receptor, <ins style="font-weight: bold; text-decoration: none;">it </ins>can <ins style="font-weight: bold; text-decoration: none;">disrupt normal synaptic transmission, leading to its characteristic </ins>dissociative effects. <ins style="font-weight: bold; text-decoration: none;">This mechanism of action is shared with </ins>other <ins style="font-weight: bold; text-decoration: none;">dissociative anesthetics </ins>such as [[ketamine]] and <ins style="font-weight: bold; text-decoration: none;">[[dextromethorphan]]</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== Effects ==</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">=</ins>== Effects <ins style="font-weight: bold; text-decoration: none;">=</ins>==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>The effects of 3-Methyl-PCPy are <del style="font-weight: bold; text-decoration: none;">primarily dissociative in nature. Users may experience </del>altered <del style="font-weight: bold; text-decoration: none;">perceptions of reality</del>, [[hallucinations]], and a <del style="font-weight: bold; text-decoration: none;">sense </del>of <del style="font-weight: bold; text-decoration: none;">detachment </del>from <del style="font-weight: bold; text-decoration: none;">the </del>environment. <del style="font-weight: bold; text-decoration: none;">The compound may also produce [[analgesic]] </del>effects<del style="font-weight: bold; text-decoration: none;">, reducing the perception </del>of <del style="font-weight: bold; text-decoration: none;">pain. However, </del>the <del style="font-weight: bold; text-decoration: none;">use </del>of <del style="font-weight: bold; text-decoration: none;">3-Methyl-PCPy can also lead to adverse effects, including [</del>[<del style="font-weight: bold; text-decoration: none;">confusion]], </del>[<del style="font-weight: bold; text-decoration: none;">[agitation</del>]]<del style="font-weight: bold; text-decoration: none;">, </del>and [[<del style="font-weight: bold; text-decoration: none;">psychosis</del>]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>The effects of 3-Methyl-PCPy are <ins style="font-weight: bold; text-decoration: none;">similar to those of PCP, including </ins>altered <ins style="font-weight: bold; text-decoration: none;">perception</ins>, [[hallucinations]], and <ins style="font-weight: bold; text-decoration: none;">[[analgesia]]. The compound can induce </ins>a <ins style="font-weight: bold; text-decoration: none;">state </ins>of <ins style="font-weight: bold; text-decoration: none;">dissociation, where users feel detached </ins>from <ins style="font-weight: bold; text-decoration: none;">their body and </ins>environment. <ins style="font-weight: bold; text-decoration: none;">These </ins>effects <ins style="font-weight: bold; text-decoration: none;">make it a subject </ins>of <ins style="font-weight: bold; text-decoration: none;">interest in </ins>the <ins style="font-weight: bold; text-decoration: none;">study </ins>of [[<ins style="font-weight: bold; text-decoration: none;">consciousness</ins>]] and [[<ins style="font-weight: bold; text-decoration: none;">psychiatric disorders</ins>]].</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Legal Status </del>==</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== <ins style="font-weight: bold; text-decoration: none;">Research Applications </ins>==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">The legal status of </del>3-Methyl-PCPy <del style="font-weight: bold; text-decoration: none;">varies by country</del>. <del style="font-weight: bold; text-decoration: none;">In many jurisdictions, it </del>is <del style="font-weight: bold; text-decoration: none;">classified </del>as <del style="font-weight: bold; text-decoration: none;">a controlled substance due to its potential for abuse </del>and <del style="font-weight: bold; text-decoration: none;">lack of accepted medical use. Researchers studying this compound must adhere to strict regulations to ensure compliance with local laws</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Due to its action on the NMDA receptor, </ins>3-Methyl-PCPy <ins style="font-weight: bold; text-decoration: none;">is used in research to study the role of glutamatergic systems in the brain</ins>. <ins style="font-weight: bold; text-decoration: none;">It </ins>is <ins style="font-weight: bold; text-decoration: none;">particularly useful in modeling conditions such </ins>as <ins style="font-weight: bold; text-decoration: none;">[[schizophrenia]] </ins>and <ins style="font-weight: bold; text-decoration: none;">[[neurodegenerative diseases]], where NMDA receptor dysfunction is implicated</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">Related Compounds </del>==</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== <ins style="font-weight: bold; text-decoration: none;">Safety and Legal Status </ins>==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>3-Methyl-PCPy is <del style="font-weight: bold; text-decoration: none;">part of a broader class </del>of <del style="font-weight: bold; text-decoration: none;">compounds known as arylcyclohexylamines</del>. <del style="font-weight: bold; text-decoration: none;">Other related compounds include:</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">As with many compounds in the arylcyclohexylamine class, </ins>3-Methyl-PCPy <ins style="font-weight: bold; text-decoration: none;">may pose risks of [[neurotoxicity]] and [[addiction]]. Its legal status varies by country, and it </ins>is <ins style="font-weight: bold; text-decoration: none;">often subject to regulation due to its potential for abuse and lack </ins>of <ins style="font-weight: bold; text-decoration: none;">approved medical use</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[Phencyclidine]] (PCP)</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== <ins style="font-weight: bold; text-decoration: none;">Related Pages </ins>==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[Ketamine]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[Methoxetamine]] (MXE)</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[Dizocilpine]] (MK-801)</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del style="font-weight: bold; text-decoration: none;">See Also </del>==</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* [[Phencyclidine]]</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[NMDA receptor antagonist]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[NMDA receptor antagonist]]</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* [[Dissociative <del style="font-weight: bold; text-decoration: none;">drug</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>* [[Dissociative <ins style="font-weight: bold; text-decoration: none;">anesthetic</ins>]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[Arylcyclohexylamine]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[Arylcyclohexylamine]]</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Related Pages ==</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[PCPy]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[Phencyclidine]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [[Ketamine]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Arylcyclohexylamines]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Arylcyclohexylamines]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Dissociative drugs]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Dissociative drugs]]</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">[[Category:NMDA receptor antagonists]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr> </table>

Prab https://wikimd.com/index.php?title=3-Methyl-PCPy&diff=6288422&oldid=prev 2025-02-11T20:33:31Z

<p>CSV import</p> <p><b>New page</b></p><div>== 3-Methyl-PCPy ==<br /> <br /> [[File:3-Me-PCPy_Structure.svg|thumb|right|Chemical structure of 3-Methyl-PCPy]]<br /> <br /> &#039;&#039;&#039;3-Methyl-PCPy&#039;&#039;&#039; is a chemical compound that belongs to the class of [[arylcyclohexylamines]]. It is a derivative of [[PCPy]], which is a [[dissociative anesthetic]] similar to [[phencyclidine]] (PCP). The compound is known for its [[NMDA receptor]] antagonistic properties, which contribute to its psychoactive effects.<br /> <br /> == Chemical Structure ==<br /> <br /> 3-Methyl-PCPy is structurally related to PCPy, with the addition of a methyl group at the third position of the [[phenyl ring]]. This modification alters its pharmacological profile, potentially affecting its potency and duration of action. The chemical structure of 3-Methyl-PCPy is depicted in the image provided.<br /> <br /> == Pharmacology ==<br /> <br /> 3-Methyl-PCPy acts primarily as an [[NMDA receptor antagonist]]. The NMDA receptor is a subtype of [[glutamate receptor]] that plays a crucial role in [[synaptic plasticity]] and [[memory function]]. By inhibiting this receptor, 3-Methyl-PCPy can induce [[dissociative]] and [[hallucinogenic]] effects. These effects are similar to those produced by other arylcyclohexylamines, such as [[ketamine]] and PCP.<br /> <br /> == Effects ==<br /> <br /> The effects of 3-Methyl-PCPy are primarily dissociative in nature. Users may experience altered perceptions of reality, [[hallucinations]], and a sense of detachment from the environment. The compound may also produce [[analgesic]] effects, reducing the perception of pain. However, the use of 3-Methyl-PCPy can also lead to adverse effects, including [[confusion]], [[agitation]], and [[psychosis]].<br /> <br /> == Legal Status ==<br /> <br /> The legal status of 3-Methyl-PCPy varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Researchers studying this compound must adhere to strict regulations to ensure compliance with local laws.<br /> <br /> == Related Compounds ==<br /> <br /> 3-Methyl-PCPy is part of a broader class of compounds known as arylcyclohexylamines. Other related compounds include:<br /> <br /> * [[Phencyclidine]] (PCP)<br /> * [[Ketamine]]<br /> * [[Methoxetamine]] (MXE)<br /> * [[Dizocilpine]] (MK-801)<br /> <br /> == See Also ==<br /> <br /> * [[NMDA receptor antagonist]]<br /> * [[Dissociative drug]]<br /> * [[Arylcyclohexylamine]]<br /> <br /> == Related Pages ==<br /> <br /> * [[PCPy]]<br /> * [[Phencyclidine]]<br /> * [[Ketamine]]<br /> <br /> [[Category:Arylcyclohexylamines]]<br /> [[Category:Dissociative drugs]]<br /> [[Category:NMDA receptor antagonists]]</div>

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