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	{{~~Short description\|A synthetic psychedelic compound}}~~		{{DISPLAYTITLE:25G-NBOMe}}
	~~{{Drugbox~~
	~~\| verifiedfields = changed~~
	~~\| verifiedrevid = 477318123~~
	~~\| IUPAC_name = 2-(4-bromo-3,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine~~
	~~\| image =~~ 25G-NBOMe~~.svg~~
	}}

	~~'''~~25G-NBOMe~~''' is a synthetic psychedelic compound that belongs to the~~ [[NBOMe~~]] series~~. ~~It is a derivative~~ of ~~the phenethylamine [[2C~~-G]] ~~and is known for its potent hallucinogenic effects.~~		== 25G-NBOMe ==
			[[File:25G-NBOMe.svg\|thumb\|right\|Chemical structure of 25G-NBOMe]]

	~~==Chemical structure and properties==~~		'''25G-NBOMe''' is a synthetic psychedelic compound that belongs to the [[NBOMe series]]. It is a derivative of the phenethylamine 2C-G and is known for its potent hallucinogenic effects. The compound is part of a class of substances that are often used in [[psychedelic research]] and recreational settings.
	25G-NBOMe is ~~chemically related~~ to the [[~~2C family~~]] ~~of psychedelic phenethylamines~~. It is ~~specifically~~ a derivative of [[2C-G~~]], with the addition~~ of a ~~2-methoxybenzyl group to the nitrogen atom, which is characteristic~~ of ~~the NBOMe series. This modification significantly increases the compound's affinity for the~~ [[~~serotonin receptor\|5-HT2A receptor~~]]~~, which is believed to be responsible for its psychedelic effects~~.

	==~~Pharmacology~~==		== Chemical Structure and Properties ==
	~~The primary mechanism of action for~~ 25G-NBOMe is ~~its agonistic activity at the [[~~5-~~HT2A receptor]], a subtype of the [[serotonin receptor]]~~. ~~This receptor~~ is ~~known to play~~ a ~~crucial role in~~ the ~~modulation~~ of ~~mood~~, ~~perception~~, ~~and cognition~~, which ~~are all affected during psychedelic experiences. The compound's high potency~~ is ~~attributed to its strong binding affinity to this receptor~~.		25G-NBOMe is chemically known as 2-(4-bromo-3,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine. It is a derivative of the 2C family of phenethylamines, specifically 2C-G, with the addition of a 2-methoxybenzyl group to the nitrogen atom, which is characteristic of the NBOMe series.

	~~==Effects==~~		The compound is typically synthesized in a laboratory setting and is known for its high potency, requiring only microgram doses to achieve its effects. This potency is due to its high affinity for the [[serotonin receptor\|5-HT2A receptor]], which is a common target for psychedelic compounds.
	The effects ~~of 25G-NBOMe are similar~~ to ~~those of other psychedelics, such as~~ [[~~LSD]] and [[psilocybin~~]]. Users report intense visual hallucinations, altered perception of time and space, and profound changes in thought processes. The onset of effects typically occurs within 30 to 90 minutes after ingestion, ~~with the experience lasting anywhere from 6 to 12 hours~~.

	==~~Risks and safety~~==		== Pharmacology ==
	25G-NBOMe~~, like other NBOMe compounds, has been associated with~~ a ~~number of adverse effects, particularly~~ at ~~higher doses. These can include [[vasoconstriction]]~~, ~~[[tachycardia]], [[hypertension]], and [[hyperthermia]]~~. ~~There have been reports of severe toxicity and fatalities associated~~ with ~~the use of NBOMe compounds~~, ~~often due~~ to ~~their high potency and the difficulty in accurately dosing them~~.		25G-NBOMe acts primarily as a partial agonist at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound may also interact with other serotonin receptors, contributing to its overall pharmacological profile.

	~~==Legal status==~~		The effects of 25G-NBOMe can include visual and auditory hallucinations, altered perception of time and space, and changes in mood and thought processes. These effects are similar to those produced by other psychedelics such as [[LSD]] and [[psilocybin]].
	The ~~legal status~~ of 25G-NBOMe ~~varies~~ by ~~country. In many jurisdictions, it is classified~~ as ~~a controlled substance due to its potential for abuse~~ and ~~lack of accepted medical use. Users should be aware of the legal implications of possessing or distributing this compound in their region~~.

	==Related ~~pages~~==		== Usage and Effects ==
			Due to its potency, 25G-NBOMe is typically administered in very small doses, often via blotter paper or as a liquid solution. Users report a range of effects, including intense visual hallucinations, euphoria, and altered sensory perception.

			The onset of effects usually occurs within 30 to 90 minutes after administration, with the peak effects lasting several hours. The total duration of the experience can vary, but it is generally in the range of 6 to 10 hours.

			== Safety and Legal Status ==
			The safety profile of 25G-NBOMe is not well-established, and there have been reports of adverse effects, particularly at higher doses. These can include [[vasoconstriction]], [[tachycardia]], [[hypertension]], and in some cases, severe psychological distress.

			Legally, 25G-NBOMe is classified as a controlled substance in many countries due to its potential for abuse and lack of accepted medical use. It is important for users to be aware of the legal status of this compound in their jurisdiction.

			== Related Pages ==
	* [[NBOMe series]]		* [[NBOMe series]]
	* [[2C family]]
	* [[Psychedelic drug]]		* [[Psychedelic drug]]
	* [[Serotonin receptor]]		* [[Serotonin receptor]]
			* [[2C family]]

	[[Category:Psychedelic phenethylamines]]		[[Category:Psychedelic phenethylamines]]
	[[Category:Serotonin receptor agonists]]		[[Category:Serotonin receptor agonists]]

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2025-02-11T20:16:36Z

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{{Short description|A synthetic psychedelic compound}}
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477318123
| IUPAC_name = 2-(4-bromo-3,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine
| image = 25G-NBOMe.svg
}}

'''25G-NBOMe''' is a synthetic psychedelic compound that belongs to the [[NBOMe]] series. It is a derivative of the phenethylamine [[2C-G]] and is known for its potent hallucinogenic effects.

==Chemical structure and properties==
25G-NBOMe is chemically related to the [[2C family]] of psychedelic phenethylamines. It is specifically a derivative of [[2C-G]], with the addition of a 2-methoxybenzyl group to the nitrogen atom, which is characteristic of the NBOMe series. This modification significantly increases the compound's affinity for the [[serotonin receptor|5-HT2A receptor]], which is believed to be responsible for its psychedelic effects.

==Pharmacology==
The primary mechanism of action for 25G-NBOMe is its agonistic activity at the [[5-HT2A receptor]], a subtype of the [[serotonin receptor]]. This receptor is known to play a crucial role in the modulation of mood, perception, and cognition, which are all affected during psychedelic experiences. The compound's high potency is attributed to its strong binding affinity to this receptor.

==Effects==
The effects of 25G-NBOMe are similar to those of other psychedelics, such as [[LSD]] and [[psilocybin]]. Users report intense visual hallucinations, altered perception of time and space, and profound changes in thought processes. The onset of effects typically occurs within 30 to 90 minutes after ingestion, with the experience lasting anywhere from 6 to 12 hours.

==Risks and safety==
25G-NBOMe, like other NBOMe compounds, has been associated with a number of adverse effects, particularly at higher doses. These can include [[vasoconstriction]], [[tachycardia]], [[hypertension]], and [[hyperthermia]]. There have been reports of severe toxicity and fatalities associated with the use of NBOMe compounds, often due to their high potency and the difficulty in accurately dosing them.

==Legal status==
The legal status of 25G-NBOMe varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Users should be aware of the legal implications of possessing or distributing this compound in their region.

==Related pages==
* [[NBOMe series]]
* [[2C family]]
* [[Psychedelic drug]]
* [[Serotonin receptor]]

[[Category:Psychedelic phenethylamines]]
[[Category:Serotonin receptor agonists]]

25G-NBOMe - Revision history

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