https://wikimd.org/index.php?action=history&feed=atom&title=18-Deoxyaldosterone 2026-04-28T22:05:32Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=18-Deoxyaldosterone&diff=2395070&oldid=prev 2021-08-06T14:05:01Z

<p>Created page with &quot;==&#039;&#039;&#039;What is {{PAGENAME}}?&#039;&#039;&#039;== <a href="/wiki/File:18-Deoxyaldosterone.svg" title="File:18-Deoxyaldosterone.svg">thumb|18-Deoxyaldosterone</a> * It is a steroidal antimineralocorticoid with mixed agonist–antagonist but predom...&quot;</p> <p><b>New page</b></p><div>==&#039;&#039;&#039;What is {{PAGENAME}}?&#039;&#039;&#039;==<br /> [[File:18-Deoxyaldosterone.svg|thumb|18-Deoxyaldosterone]]<br /> * It is a steroidal antimineralocorticoid with mixed agonist–antagonist but predominantly antagonistic activity at the mineralocorticoid receptor&lt;ref&gt;Duax WL, Griffin JF, Strong PD, Funder JW, Ulick S (1982). &quot;Molecular structure of 18-deoxyaldosterone and its relationship to receptor binding and activity&quot;. &#039;&#039;Journal of the American Chemical Society&#039;&#039;. &#039;&#039;&#039;104&#039;&#039;&#039; (25): 7291–7293. doi:10.1021/ja00389a063 [https://pubs.acs.org/doi/abs/10.1021/ja00389a063].&lt;/ref&gt;.<br /> *&#039;&#039;&#039;IUPAC Name&#039;&#039;&#039;: &#039;&#039;(2S,5S,6S,14R,15S,16S)-2-(2-hydroxyacetyl)-14-methyl-17-oxapentacyclo[14.2.1.01,5.06,15.09,14]nonadec-9-en-11-one&#039;&#039;<br /> *&#039;&#039;&#039;InChI&#039;&#039;&#039;: &#039;&#039;InChI=1S/C21H28O4/c1-20-7-6-13(23)8-12(20)2-3-14-15-4-5-16(17(24)10-22)21(15)9-18(19(14)20)25-11-21/h8,14-16,18-19,22H,2-7,9-11H2,1H3/t14-,15-,16+,18-,19+,20-,21?/m0/s1&#039;&#039;<br /> *&#039;&#039;&#039;InChI Key&#039;&#039;&#039;: &#039;&#039;ZEBLTAXSHAKMDJ-QBSCYWOBSA-N&#039;&#039;<br /> *&#039;&#039;&#039;Canonical SMILES&#039;&#039;&#039;: &#039;&#039;CC12CCC(=O)C=C1CCC3C2C4CC5(C3CCC5C(=O)CO)CO4&#039;&#039;<br /> *&#039;&#039;&#039;Isomeric SMILES&#039;&#039;&#039;: &#039;&#039;C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@@H]4CC5([C@H]3CC[C@@H]5C(=O)CO)CO4&#039;&#039;<br /> *&#039;&#039;&#039;Molecular formula&#039;&#039;&#039;: &#039;&#039;C21H28O4&#039;&#039;<br /> *&#039;&#039;&#039;Molecular weight&#039;&#039;&#039;: &#039;&#039;344.4 g·mol−1&#039;&#039;<br /> *&#039;&#039;&#039;PubChem CID&#039;&#039;&#039;: &#039;&#039;188963&#039;&#039;<br /> *&#039;&#039;&#039;Synonyms&#039;&#039;&#039;:<br /> # &#039;&#039;DTXSID30947934&#039;&#039;<br /> # &#039;&#039;21-Hydroxy-11,18-epoxypregn-4-ene-3,20-dione&#039;&#039;<br /> &lt;ref&gt;National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 188963, 18-Deoxyaldosterone. Retrieved August 6, 2021 from [https://pubchem.ncbi.nlm.nih.gov/compound/18-Deoxyaldosterone].&lt;/ref&gt;<br /> <br /> ==References==<br /> {{reflist}}<br /> <br /> {{Mineralocorticoid receptor modulators}}<br /> <br /> [[Category:Primary alcohols]]<br /> [[Category:Antimineralocorticoids]]<br /> [[Category:Diketones]]<br /> [[Category:Pregnanes]]<br /> [[Category:Enones]]<br /> <br /> {{steroid-stub}}</div>

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