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16-Hydroxyestradiol - Revision history
2026-04-25T20:33:14Z
Revision history for this page on the wiki
MediaWiki 1.44.2
https://wikimd.org/index.php?title=16-Hydroxyestradiol&diff=6527255&oldid=prev
Prab at 17:09, 18 March 2025
2025-03-18T17:09:12Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:09, 18 March 2025</td>
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Prab
https://wikimd.org/index.php?title=16-Hydroxyestradiol&diff=6496309&oldid=prev
Prab: CSV import
2025-03-17T02:47:12Z
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Prab
https://wikimd.org/index.php?title=16-Hydroxyestradiol&diff=6202070&oldid=prev
Prab: CSV import
2025-02-10T04:45:59Z
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Prab
https://wikimd.org/index.php?title=16-Hydroxyestradiol&diff=5390865&oldid=prev
Prab: CSV import
2024-03-11T07:20:34Z
<p>CSV import</p>
<p><b>New page</b></p><div>'''16-Hydroxyestradiol''' (also known as '''16α-Hydroxyestradiol''') is a [[metabolite]] of [[estradiol]], an important [[female sex hormone]]. It is formed in the body by the action of the enzyme [[cytochrome P450]] on estradiol. <br />
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==Structure and Properties==<br />
16-Hydroxyestradiol is a [[steroid]] hormone, like all [[estrogen]]s. It has a molecular weight of 302.4 g/mol and a molecular formula of C18H24O3. Its structure includes a hydroxyl group (-OH) at the 16α position on the estradiol molecule, hence its name.<br />
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==Biological Role==<br />
16-Hydroxyestradiol is one of several metabolites of estradiol that have biological activity. It binds to the [[estrogen receptor]], a protein found in many tissues of the body, including the [[breast]], [[uterus]], and [[brain]]. By binding to this receptor, 16-Hydroxyestradiol can influence the growth and development of these tissues.<br />
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==Health Implications==<br />
Research has suggested that 16-Hydroxyestradiol may have a role in the development of certain diseases. For example, it has been implicated in the development of [[breast cancer]] and [[endometriosis]]. However, more research is needed to fully understand these potential links.<br />
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==See Also==<br />
* [[Estradiol]]<br />
* [[Estrogen receptor]]<br />
* [[Breast cancer]]<br />
* [[Endometriosis]]<br />
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==References==<br />
<references /><br />
<br />
[[Category:Estrogens]]<br />
[[Category:Steroid hormones]]<br />
[[Category:Metabolites]]<br />
[[Category:Endocrinology]]<br />
[[Category:Oncology]]<br />
[[Category:Gynecology]]<br />
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{{medicine-stub}}</div>
Prab