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Myelin
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'''Myelin''' is a fatty substance that surrounds the axon of some nerve cells, forming an electrically insulating layer. It is essential for the proper functioning of the nervous system. It is an outgrowth of a type of glial cell. The production of the myelin sheath is called myelination or myelinogenesis. ==Structure== Myelin is composed of about 40% water; the dry mass is about 70β85% lipids and about 15β30% proteins. Some of the proteins that make up myelin are [[Myelin basic protein|Myelin basic protein (MBP)]], [[Myelin oligodendrocyte glycoprotein|Myelin oligodendrocyte glycoprotein (MOG)]], and [[Proteolipid protein|Proteolipid protein (PLP)]]. The most important lipids of myelin are [[cholesterol]], [[phospholipid]]s, and [[galactocerebroside]]s. ==Function== The main role of a myelin layer (or sheath) is to increase the speed at which impulses propagate along the [[myelinated fiber]]. Along unmyelinated fibers, impulses move continuously as waves, but, in myelinated fibers, they hop or "propagate by [[Saltatory conduction|saltatory conduction]]". ==Clinical significance== Demyelination is the loss of the myelin sheath insulating the nerves, and is the hallmark of some neurodegenerative autoimmune diseases, including [[multiple sclerosis]] and [[acute disseminated encephalomyelitis]]. ==See also== * [[Neuron]] * [[Nervous system]] * [[Neuroscience]] ==References== <references /> [[Category:Neuroanatomy]] [[Category:Neurophysiology]] [[Category:Cell biology]] [[Category:Membrane biology]] [[Category:Neurology]] {{stub}} == Myelin == <gallery> File:Myelinated neuron.jpg|Myelinated neuron File:Myelin sheath (1).svg|Myelin sheath File:Saltatory Conduction.gif|Saltatory conduction </gallery>
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