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Limbus
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'''Limbus''' is a border or edge that is often referred to in medical terminology. In ophthalmology, the limbus is the border between the cornea and the sclera. The limbus is a crucial area of the eye as it is responsible for the regeneration of the cornea. == Anatomy == The limbus is located at the junction of the [[cornea]] and the [[sclera]]. It is a complex structure that is composed of several different tissues. The limbus contains the corneal epithelial stem cells which are essential for the maintenance and repair of the corneal surface. == Function == The primary function of the limbus is to act as a barrier to prevent the invasion of the conjunctival epithelial cells onto the cornea. It also plays a crucial role in the maintenance of the corneal transparency by preventing the vascularization of the cornea. == Clinical significance == Damage to the limbus can lead to a condition known as [[limbal stem cell deficiency]] (LSCD). This condition can result in pain, loss of vision, and may require a [[limbal stem cell transplantation]] for treatment. == See also == * [[Cornea]] * [[Sclera]] * [[Limbal stem cell deficiency]] * [[Limbal stem cell transplantation]] == References == <references /> [[Category:Eye]] [[Category:Anatomy]] [[Category:Ophthalmology]] {{Eye anatomy}} {{Anatomy-stub}} {{No image}}
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