Editing FGF2

'''FGF2‏‎''' or '''Fibroblast Growth Factor 2''' is a type of [[protein]] and a member of the [[Fibroblast Growth Factor]] (FGF) family. It is also known as '''basic fibroblast growth factor''' (bFGF) and '''FGF-β'''. FGF2‏‎ plays a crucial role in [[cell proliferation]], [[cell differentiation]], and [[angiogenesis]], which is the formation of new blood vessels from pre-existing ones.

== Function ==

FGF2‏‎ is a potent modulator of [[cell growth]] and [[cell differentiation]]. It is involved in a variety of biological processes, including [[embryonic development]], [[tissue repair]], [[tumor growth]], and [[invasion]]. FGF2‏‎ achieves its functions by binding to its receptors, known as [[FGF receptors]] (FGFRs), which triggers a cascade of downstream [[signal transduction]] pathways.

== Structure ==

FGF2‏‎ is a single-chain [[polypeptide]] composed of 146 amino acids. It lacks a signal peptide, which is unusual for a secreted protein. Instead, FGF2‏‎ is exported from cells by a non-classical pathway, which is not yet fully understood.

== Clinical Significance ==

Due to its role in cell growth and differentiation, FGF2‏‎ has been implicated in a variety of diseases, including [[cancer]], [[diabetes]], and [[atherosclerosis]]. It is also being investigated for its potential use in [[tissue engineering]] and [[regenerative medicine]].

== See Also ==

* [[Fibroblast Growth Factor]]
* [[FGF receptors]]
* [[Angiogenesis]]
* [[Signal transduction]]

== References ==

<references />

{{protein-stub}}
[[Category:Growth factors]]
[[Category:Cell biology]]
[[Category:Proteins]]
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