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Chorea
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{{SI}} {{Infobox medical condition | name = Chorea | image = [[File:Hereditary_chorea,_year_5.jpg|250px]] | caption = A patient exhibiting symptoms of hereditary chorea | field = [[Neurology]] | symptoms = [[Involuntary movements]], [[muscle weakness]], [[clumsiness]] | complications = [[Falls]], [[injuries]], [[social isolation]] | onset = Varies by type; can be [[childhood]] or [[adulthood]] | duration = Can be [[chronic]] or [[progressive]] | types = [[Huntington's disease]], [[Sydenham's chorea]], [[Chorea gravidarum]] | causes = [[Genetic mutations]], [[autoimmune reactions]], [[pregnancy]] | risks = [[Family history]], [[rheumatic fever]], [[pregnancy]] | diagnosis = [[Clinical examination]], [[genetic testing]], [[imaging studies]] | differential = [[Tardive dyskinesia]], [[athetosis]], [[dystonia]] | prevention = Depends on type; [[genetic counseling]] for hereditary forms | treatment = [[Medications]], [[physical therapy]], [[occupational therapy]] | medication = [[Tetrabenazine]], [[antipsychotics]], [[benzodiazepines]] | prognosis = Varies; [[progressive]] in some forms like [[Huntington's disease]] | frequency = Rare; varies by type }} ==Chorea== [[File:Hereditary chorea, year 5.jpg|thumb|300px|Hereditary_chorea,_year_5]] Chorea is a neurological condition characterized by involuntary, irregular muscle movements that are brief, non-repetitive, and unpredictable. This disorder affects the body's motor functions, leading to fluid and dance-like movements that can impact various parts of the body. Chorea is notably associated with [[Huntington's disease]], but it can also arise from a variety of other conditions. ==Causes== <youtube> title='''{{PAGENAME}}''' movie_url=http://www.youtube.com/v/qZSVlGN_EOI &rel=1 embed_source_url=http://www.youtube.com/v/qZSVlGN_EOI &rel=1 wrap = yes width=750 height=600 </youtube> Chorea can be caused by several factors, including: * Genetic disorders, with [[Huntington's disease]] being the most well-known cause. * Autoimmune diseases, such as [[Sydenham's chorea]], which is associated with rheumatic fever. * Metabolic disorders. * Drug-induced chorea, resulting from the side effects of certain medications. * Infections and other conditions affecting the brain. ==Symptoms== Symptoms of chorea include: * Involuntary movements that are rapid, jerky, and unpredictable. * Muscle weakness and coordination problems. * Difficulty maintaining posture and balance. * Changes in gait and facial expressions. ===Diagnosis=== Diagnosis of chorea involves: * Clinical evaluation of the symptoms. * Neurological examination. * Genetic testing, especially for conditions like Huntington's disease. * Imaging studies, such as MRI or CT scans, to observe brain structure and function. * Blood tests to identify possible metabolic or autoimmune causes. ===Treatment=== While there is no cure for chorea, treatment focuses on managing symptoms and may include: * Medications to reduce involuntary movements, such as antipsychotics or benzodiazepines. * Therapies to improve motor skills and manage physical symptoms. * Supportive care for emotional and psychological well-being. ===Association with Huntington's Disease=== Huntington's disease is a genetic disorder that leads to the progressive degeneration of nerve cells in the brain. Chorea is a hallmark symptom of Huntington's, along with cognitive decline and psychiatric issues. Understanding and managing chorea is crucial in the overall care for patients with Huntington's disease. ==External Links== * [https://www.ninds.nih.gov/Disorders/All-Disorders/Chorea-Information-Page National Institute of Neurological Disorders and Stroke (NINDS) - Chorea Information Page] * [https://hdsa.org/ Huntington's Disease Society of America (HDSA)] [[Category:Neurological disorders]] [[Category:Symptoms and signs: Nervous system]] {{stub}} {{dictionary-stub1}}
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