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25-NB
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== 25-NB == [[File:25-NB-structure-general.png|thumb|General structure of 25-NB compounds]] '''25-NB''' refers to a class of [[psychedelic]] [[phenethylamines]] that are derived from the 2C family of compounds. These substances are known for their potent [[hallucinogenic]] effects and have been used in both recreational and research settings. The "NB" in the name stands for "N-benzyl," indicating the presence of a benzyl group attached to the nitrogen atom of the phenethylamine backbone. == Structure and Chemistry == The general structure of 25-NB compounds includes a phenethylamine core with a methoxy group at the 2 and 5 positions of the benzene ring, and a benzyl group attached to the nitrogen atom. This structure is responsible for the unique pharmacological properties of these compounds. === Variants === Several variants of 25-NB compounds exist, each with different substituents on the benzyl group, leading to variations in their effects and potency. Some of the notable variants include: * '''25B-NB''' * '''25C-NB''' * '''25I-NB''' === 2C-I-NBOMe === [[File:2C-I-NBOMe-skeletal.svg|thumb|Structure of 2C-I-NBOMe]] 2C-I-NBOMe is one of the most well-known derivatives of the 25-NB series. It is known for its high potency and has been used in both recreational and research contexts. == Pharmacology == 25-NB compounds act primarily as agonists at the [[serotonin receptor|5-HT2A receptor]], which is believed to be responsible for their psychedelic effects. The presence of the N-benzyl group significantly increases the affinity of these compounds for the receptor, making them much more potent than their 2C counterparts. == Effects == The effects of 25-NB compounds can vary widely depending on the specific variant and dosage. Common effects include: * Visual and auditory hallucinations * Altered perception of time and space * Enhanced mood and euphoria * Increased sensory awareness == Safety and Legal Status == Due to their high potency and potential for adverse effects, many 25-NB compounds are classified as controlled substances in various countries. Users should exercise caution and be aware of the legal status of these substances in their region. == Related Pages == * [[Phenethylamine]] * [[Psychedelic drug]] * [[Serotonin receptor]] * [[2C family]] == Gallery == <gallery> File:25B-NB_structure.png|Structure of 25B-NB File:25C-NB_structure.png|Structure of 25C-NB File:25I-NB_structure.png|Structure of 25I-NB File:25I-NMeTh_structure.png|Structure of 25I-NMeTh File:25B-NMePyr_structure.png|Structure of 25B-NMePyr File:25I-NMeFur_structure.png|Structure of 25I-NMeFur File:25I-NMeTHF_structure.png|Structure of 25I-NMeTHF File:25B-NBF.svg|Structure of 25B-NBF File:25B-NBOH_structure.png|Structure of 25B-NBOH </gallery> [[Category:Psychedelic phenethylamines]] == 25-NB == <gallery> File:25-NB-structure-general.png|25-NB File:2C-I-NBOMe-skeletal.svg|2C-I-NBOMe skeletal structure File:25B-NB_structure.png|25B-NB structure File:25C-NB_structure.png|25C-NB structure File:25I-NB_structure.png|25I-NB structure File:25I-NMeTh_structure.png|25I-NMeTh structure File:25B-NMePyr_structure.png|25B-NMePyr structure File:25I-NMeFur_structure.png|25I-NMeFur structure File:25I-NMeTHF_structure.png|25I-NMeTHF structure File:25B-NBF.svg|25B-NBF File:25B-NBOH_structure.png|25B-NBOH structure File:2C-B-NBOMe-skeletal.svg|2C-B-NBOMe skeletal structure </gallery> <gallery> File:25-NB-structure-general.png|25-NB File:2C-I-NBOMe-skeletal.svg|2C-I-NBOMe File:25B-NB_structure.png|25B-NB File:25C-NB_structure.png|25C-NB File:25I-NB_structure.png|25I-NB File:25I-NMeTh_structure.png|25I-NMeTh File:25B-NMePyr_structure.png|25B-NMePyr File:25I-NMeFur_structure.png|25I-NMeFur File:25I-NMeTHF_structure.png|25I-NMeTHF File:25B-NBF.svg|25B-NBF File:25B-NBOH_structure.png|25B-NBOH File:2C-B-NBOMe-skeletal.svg|2C-B-NBOMe </gallery>
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