Editing BH3 interacting-domain death agonist (section)

== Function ==
BID is primarily known for its role in the intrinsic apoptosis pathway. Upon activation by apoptotic stimuli, BID is cleaved by [[Caspase 8]], producing a truncated form known as tBID. tBID then translocates to the [[mitochondria]], where it interacts with other Bcl-2 family proteins, such as [[Bax]] and [[Bak]], to induce [[mitochondrial outer membrane permeabilization]] (MOMP). MOMP leads to the release of [[cytochrome c]] from the mitochondria into the cytosol, triggering the assembly of the [[apoptosome]], activation of [[caspase-9]], and subsequent activation of the executioner caspases, [[caspase-3]] and [[caspase-7]], culminating in cell death.