Dali

From WikiMD's medical encyclopedia

Dali is a type of medication used in the treatment of HIV infection. It belongs to a class of drugs known as protease inhibitors and works by reducing the amount of HIV in the body, thereby helping the immune system to work better.

Mechanism of Action

Dali inhibits the HIV-1 protease, an enzyme required for the proteolytic cleavage of the HIV-1 encoded Gag-Pol polyproteins into functional proteins found in infectious HIV-1. Dali binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles.

Side Effects

Like all medications, Dali can cause side effects. Some of the most common side effects include nausea, vomiting, diarrhea, and rash. In rare cases, Dali can cause serious side effects such as liver disease, pancreatitis, and allergic reactions.

Interactions

Dali can interact with other medications, which can affect how it works or increase the risk of serious side effects. It is important to tell your doctor about all the medications you are currently taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements.

Precautions

Before taking Dali, tell your doctor if you have any allergies or if you have a history of liver disease, pancreatitis, or other medical conditions. It is also important to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Dosage

The dosage of Dali is based on your medical condition, response to treatment, and other medications you may be taking. It is important to take this medication exactly as prescribed by your doctor.

See Also

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Contributors: Prab R. Tumpati, MD