Difference between revisions of "Mast cell"

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(Created page with "Mast cell is a type of cell present in most body tissues that releases substances in response to an allergen, which causes symptoms such as inflammation {{stub}}")
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{{Infobox cell
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Mast cell is a type of cell present in most [[body]] tissues that releases substances in response to an allergen, which causes symptoms such as [[inflammation]]  
| Name        = Mast cell
 
| Latin      = mastocytus
 
| Greek      =
 
| Image      = SMCpolyhydroxysmall.jpg
 
| Caption    = Mast cells
 
| Width      =
 
| Image2      =
 
| Caption2    =
 
| Precursor  =
 
| System      = [[Immune system]]
 
}}
 
[[Image:Mast cell.png|thumb|Mast cell]]
 
  
A '''mast cell''' is like a [[white blood cell]] (leukocyte) which lives and acts in [[Tissue (biology)|tissues]]. It is made in [[bone marrow]], and matures in tissues, where it defends against parasites.
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Mast cells have many [[Granule (cell biology)|granules]] rich in [[histamine]] and [[heparin]]. Mast cells play an important protective role  in wound healing and defence against [[pathogen]]s.<ref name=Prussin>{{cite journal |author=Prussin C, Metcalfe DD |title=IgE, mast cells, basophils, and eosinophils |journal=J Allergy Clin Immunol |volume=111 |issue=2 Suppl |pages=S486–94 |year=2003 |pmid=12592295|doi=10.1067/mai.2003.120}}</ref> They are a part cause of [[allergy]] and [[anaphylaxis]],
 
 
 
The mast cell is very similar in both appearance and function to the [[Basophil granulocyte|basophil]], a type of [[white blood cell]]. However, they are not the same.  <ref>Marieb, Elaine N. & Katja Hoehn. 2007. ''Human anatomy and physiology''. 7th ed, San Francisco: Pearson Benjamin Cummings,  659.</ref>
 
 
 
Mast cells were first described by [[Paul Ehrlich]] in his 1878 doctoral thesis. He noted the large granules visible once they were stained.<ref>Ehrlich P. 1878. ''Beiträge zur Theorie und Praxis der histologischen Färbung.'' Dissertation at Leipzig University.</ref>  They are now considered to be part of the [[immune system]].
 
 
 
== References ==
 
{{Reflist}}
 
 
 
 
 
 
 
[[Category:Cells]]
 
[[Category:Immunology]]
 

Revision as of 14:35, 22 March 2019

Mast cell is a type of cell present in most body tissues that releases substances in response to an allergen, which causes symptoms such as inflammation


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