Zuclomifene

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Zuclomifene

Zuclomifene (pronounced: zoo-KLOM-ih-feen) is a pharmaceutical drug used in the field of oncology and reproductive medicine. It is a nonsteroidal selective estrogen receptor modulator (SERM) that has both agonist and antagonist properties.

Etymology

The term "Zuclomifene" is derived from its chemical name, (Z)-2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine. The prefix "Zu-" is a reference to the Z-isomer of the drug, which is one of the two forms of the drug that exist due to its chirality.

Usage

Zuclomifene is primarily used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. It is also used in the treatment of infertility in women, as it can induce ovulation by blocking the negative feedback of estrogen at the hypothalamus.

Related Terms

  • Clomifene: A related drug that also acts as a selective estrogen receptor modulator. It is primarily used in the treatment of female infertility.
  • Tamoxifen: Another related drug that is used in the treatment of estrogen receptor-positive breast cancer.
  • Selective estrogen receptor modulator: A type of drug that has selective activity on estrogen receptors.

Side Effects

Like all drugs, Zuclomifene can have side effects. These can include nausea, vomiting, breast tenderness, and blurred vision. In rare cases, it can cause ovarian hyperstimulation syndrome, a potentially serious condition.

See Also

External links

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