Walthard cell rest

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Walthard Cell Rest

Walthard cell rest (pronunciation: /ˈwɔːlθɑːrd sɛl rɛst/) is a term used in histopathology to describe a specific type of epithelial cell found in the ovary and parovarian region. These cells are remnants of the mesonephric duct and are often found in the broad ligament of the uterus.

Etymology

The term "Walthard cell rest" is named after Swiss pathologist Max Walthard, who first described these cells in the early 20th century.

Description

Walthard cell rests are small, round or oval cells with a high nucleus-to-cytoplasm ratio. They are often found in clusters or nests and are typically non-ciliated. These cells are considered benign and are often incidental findings during histopathological examination of the ovary or parovarian region.

Clinical Significance

While Walthard cell rests are typically benign, they can occasionally give rise to benign cystic lesions or, rarely, malignant neoplasms. The most common type of neoplasm arising from Walthard cell rests is the benign Brenner tumor.

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