Vosaroxin
Vosaroxin
Vosaroxin (pronounced vo-sa-rox-in) is a quinolone derivative that functions as an anticancer agent. It is a first-in-class anticancer quinolone derivative (AQD), a class of compounds that has not been used previously for the treatment of cancer.
Etymology
The term "Vosaroxin" is a coined name for this specific drug. The prefix "Vosa-" is arbitrary, while "-roxin" is a common suffix for drugs in the quinolone family.
Mechanism of Action
Vosaroxin intercalates DNA and inhibits Topoisomerase II, leading to site-specific DNA damage, G2 arrest, and apoptosis.
Clinical Use
Vosaroxin is being investigated for use in a variety of malignancies, including acute myeloid leukemia (AML) and ovarian cancer.
Related Terms
External links
- Medical encyclopedia article on Vosaroxin
- Wikipedia's article - Vosaroxin
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