Veliparib

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Veliparib
TermVeliparib
Short definitionveliparib - (pronounced) (veh-lih-PAR-ib) substance being studied to treat breast cancer caused by mutations (changes) in the BRCA1 and BRCA2 genes. It is also being studied in the treatment of other types of cancer. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


veliparib - (pronounced) (veh-lih-PAR-ib) substance being studied to treat breast cancer caused by mutations (changes) in the BRCA1 and BRCA2 genes. It is also being studied in the treatment of other types of cancer. It blocks an enzyme involved in many cell functions, including repairing DNA damage. DNA damage can be caused by normal cell action, UV light, some cancer drugs, and radiation used to treat cancer. Veliparib can cause cancer cells to die. It is a type of poly(ADP-ribose) polymerase inhibitor. Also called ABT-888 and PARP-1 inhibitor ABT-888

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