Unipolar depression

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Unipolar Depression

Unipolar depression, also known as Major Depressive Disorder (MDD), is a common and serious medical illness that negatively affects how you feel, the way you think and how you act.

Pronunciation

Unipolar depression is pronounced as "yoo-nee-poh-lar de-pre-shun".

Etymology

The term "unipolar depression" is derived from the Latin words "uni" meaning "one" and "polar" meaning "pole". This refers to the single pole or direction of mood, which is down in the case of unipolar depression.

Definition

Unipolar depression is characterized by a persistent feeling of sadness or a lack of interest in outside stimuli. The term "unipolar" refers to the presence of one pole, or one state of mood, which is depression. This differentiates it from bipolar disorder, which refers to the presence of two poles, or two states of mood, which are depression and mania.

Symptoms

Symptoms of unipolar depression can vary among individuals but generally include feelings of sadness, hopelessness, and a loss of interest in activities once enjoyed. Other symptoms may include changes in appetite or weight, sleep disturbances, loss of energy, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of death or suicide.

Causes

The exact cause of unipolar depression is unknown, but it is believed to be a combination of genetic, biological, environmental, and psychological factors. It is often associated with changes in the brain’s neurotransmitter levels, particularly serotonin and norepinephrine.

Treatment

Treatment for unipolar depression typically involves a combination of medication, psychotherapy, and lifestyle changes. Medications used to treat unipolar depression include antidepressants, which work by balancing chemicals in the brain that affect mood and emotions.

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