Umeclidinium bromide

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Umeclidinium bromide

Umeclidinium bromide (pronounced as yoo mek li DIN ee um BROE mide) is a long-acting muscarinic antagonist (LAMA) used in the management of chronic obstructive pulmonary disease (COPD). It is marketed under the brand name Incruse Ellipta among others.

Etymology

The name "Umeclidinium bromide" is derived from its chemical structure. "Umeclidinium" is a combination of parts of the names of its chemical constituents, and "bromide" refers to the bromine atom present in the compound.

Pharmacology

Umeclidinium bromide is a bronchodilator that works by relaxing the muscles in the airways and increasing the flow of air to the lungs. It is a type of drug known as a long-acting muscarinic antagonist (LAMA), which blocks the action of acetylcholine, a neurotransmitter that can cause the airways to constrict.

Usage

Umeclidinium bromide is used as a maintenance treatment for chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It is not used to relieve sudden breathing problems and will not replace a rescue inhaler.

Side Effects

Common side effects of Umeclidinium bromide include upper respiratory tract infection, stuffy or runny nose, cough, mouth or throat pain, joint pain, changes in your voice, and constipation. Serious side effects may include allergic reactions, urinary retention, and worsening of narrow-angle glaucoma.

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