Tyrocidine
Tyrocidine
Tyrocidine (pronounced: tie-row-sid-een) is a cyclic decapeptide antibiotic that is produced by the bacterium Bacillus brevis. It was one of the first antibiotics to be discovered and is notable for its broad spectrum of activity.
Etymology
The term "Tyrocidine" is derived from the Greek words "tyros" meaning cheese and "cide" meaning to kill. This is in reference to the fact that Bacillus brevis, the bacterium that produces Tyrocidine, is commonly found in soil and spoiled food, including cheese.
Function
Tyrocidine functions by disrupting the bacterial cell membrane, leading to a loss of membrane potential and eventually cell death. It is effective against both Gram-positive and Gram-negative bacteria, making it a broad-spectrum antibiotic.
Related Terms
- Antibiotic: A substance that inhibits the growth of or destroys microorganisms.
- Bacillus brevis: A species of bacterium that produces Tyrocidine.
- Cell membrane: The semipermeable membrane surrounding the cytoplasm of a cell.
- Gram-positive bacteria: Bacteria that give a positive result in the Gram stain test.
- Gram-negative bacteria: Bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation.
See Also
- Polymyxin: Another antibiotic produced by Bacillus brevis.
- Gram stain: A method of staining bacterial cells to identify and classify them.
External links
- Medical encyclopedia article on Tyrocidine
- Wikipedia's article - Tyrocidine
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