Tubulointerstitial nephritis
Tubulointerstitial nephritis
Tubulointerstitial nephritis (pronunciation: too-buh-loh-in-tur-stish-ul nuh-fry-tis) is a form of nephritis that affects the interstitium and tubules of the kidneys.
Etymology
The term "tubulointerstitial nephritis" is derived from the Latin words "tubulus" meaning tube, "interstitium" meaning space or interval, and "nephros" meaning kidney. The suffix "-itis" is derived from Greek and signifies inflammation. Thus, the term refers to the inflammation of the interstitial and tubular parts of the kidneys.
Definition
Tubulointerstitial nephritis is a disease characterized by inflammation of the renal tubules and interstitium, the spaces between the renal tubules. This condition can lead to kidney failure if not treated promptly.
Symptoms
Symptoms of tubulointerstitial nephritis may include fatigue, nausea, vomiting, weight loss, and changes in urine output. In some cases, the disease may be asymptomatic, meaning it does not produce any symptoms.
Causes
Tubulointerstitial nephritis can be caused by a variety of factors, including certain medications, infections, autoimmune diseases, and genetic disorders.
Diagnosis
Diagnosis of tubulointerstitial nephritis typically involves a combination of blood tests, urine tests, and imaging studies. In some cases, a kidney biopsy may be necessary to confirm the diagnosis.
Treatment
Treatment for tubulointerstitial nephritis typically involves addressing the underlying cause of the disease. This may involve discontinuing certain medications, treating infections, or managing autoimmune diseases. In severe cases, dialysis or a kidney transplant may be necessary.
Related Terms
External links
- Medical encyclopedia article on Tubulointerstitial nephritis
- Wikipedia's article - Tubulointerstitial nephritis
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