Transient acantholytic dermatosis

Transient acantholytic dermatosis (pronounced: tran-zee-uhnt a-kan-tho-ly-tik der-muh-toh-sis), also known as Grover's disease, is a skin condition characterized by the sudden onset of red, itchy bumps on the skin. The etymology of the term is derived from the Greek words "akantha" meaning thorn and "lysis" meaning loosening, referring to the characteristic histological finding of acantholysis in the skin.

Definition

Transient acantholytic dermatosis is a condition that primarily affects middle-aged and elderly individuals, particularly men. It is characterized by the sudden onset of red, itchy bumps on the skin, typically on the chest and back. The exact cause of this condition is unknown, but it is thought to be related to increased sweating and heat.

Symptoms

The primary symptom of transient acantholytic dermatosis is the appearance of small, red, itchy bumps on the skin. These bumps, or papules, may also be filled with a clear fluid (vesicles). The rash is typically located on the chest and back, but it can also appear on other parts of the body.

Diagnosis

The diagnosis of transient acantholytic dermatosis is typically made based on the characteristic appearance of the rash. A skin biopsy may also be performed, which will show acantholysis, or the breakdown of the cells in the outermost layer of the skin.

Treatment

Treatment for transient acantholytic dermatosis primarily involves managing the symptoms. This may include the use of topical corticosteroids to reduce inflammation and itching. In severe cases, oral medications may be necessary.

Related Terms

• Acantholysis
• Grover's disease
• Papules
• Vesicles

External links

• Medical encyclopedia article on Transient acantholytic dermatosis
• Wikipedia's article - Transient acantholytic dermatosis

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