Tiopronin

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Tiopronin

Tiopronin (pronounced tee-o-pro-nin) is a medication used primarily in the treatment of cystinuria, a genetic disorder that causes the buildup of an amino acid called cystine in the kidneys and bladder, leading to the formation of cystine stones.

Etymology

The term "Tiopronin" is derived from the chemical name of the drug, which is N-(2-mercaptopropionyl)glycine. The "Tio" part of the name comes from the Spanish word for sulfur, reflecting the presence of a sulfur atom in the molecule. The "pronin" part of the name is a combination of "propionyl" and "glycine", two components of the chemical structure of the drug.

Usage

Tiopronin is used to prevent kidney stones in people with cystinuria. It works by reducing the amount of cystine in the urine, which in turn reduces the likelihood of stone formation. It is usually taken orally, in tablet form, and is often prescribed alongside other treatments such as increased fluid intake and dietary changes.

Related Terms

  • Cystinuria: A genetic disorder that causes an excess of the amino acid cystine in the urine, leading to the formation of cystine stones in the kidneys and bladder.
  • Kidney stone: A hard, crystalline mineral material formed within the kidney or urinary tract.
  • Amino acid: Organic compounds that combine to form proteins. Amino acids and proteins are fundamental components of all living cells.
  • Cystine: An amino acid that occurs in most proteins. It is notable for forming disulfide bonds, which contribute to the folding and stability of some proteins.

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