Thebaine
Thebaine
Thebaine (pronounced /ˈθiːbeɪn/), also known as paramorphine, is an opiate alkaloid. It is a minor constituent of opium, which is obtained from the poppy plant (Papaver somniferum). Thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effects, making it more similar to amphetamines in its effects.
Etymology
The term "Thebaine" is derived from the Greek city of Thebes, the capital of the ancient region of Boeotia, where the poppy plant was widely cultivated in antiquity.
Pharmacology
Thebaine is a potent analgesic, but is also highly addictive. It is used in the manufacture of semi-synthetic opioid drugs such as oxycodone and hydrocodone, which are used for the treatment of acute and chronic pain. Thebaine is also used in the production of naloxone, a drug used to treat opioid overdoses.
Related Terms
- Opiate: A drug derived from opium.
- Alkaloid: A class of naturally occurring organic compounds that contain mostly basic nitrogen atoms.
- Morphine: A powerful opiate used in medicine for its analgesic and sedative effects.
- Codeine: A less potent opiate used in medicine primarily for its analgesic and antitussive effects.
- Amphetamine: A potent central nervous system stimulant.
- Oxycodone: A semi-synthetic opioid derived from thebaine, used for the treatment of moderate to severe pain.
- Hydrocodone: A semi-synthetic opioid derived from thebaine, used for the treatment of moderate to severe pain.
- Naloxone: A drug used to counter the effects of opioid overdose.
External links
- Medical encyclopedia article on Thebaine
- Wikipedia's article - Thebaine
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