Tetrahydrofolate
Tetrahydrofolate
Tetrahydrofolate (pronunciation: te-tra-hy-dro-fo-late) is a form of the vitamin folate that plays a crucial role in many biological functions. It is also known as THF.
Etymology
The term "Tetrahydrofolate" is derived from the Greek words "tetra" meaning four, "hydro" indicating the presence of hydrogen, and "folate" referring to the vitamin B complex.
Function
Tetrahydrofolate is involved in the transfer of single-carbon units in the metabolism of nucleic acids and amino acids. It is essential for the synthesis of DNA, RNA, and proteins.
Related Terms
- Folate: The naturally occurring form of the vitamin B9 found in many foods. Tetrahydrofolate is the active form of this vitamin in the body.
- Methylenetetrahydrofolate: A derivative of tetrahydrofolate that is involved in the synthesis of thymine, a component of DNA.
- Methionine: An essential amino acid that requires tetrahydrofolate for its synthesis.
- Homocysteine: An amino acid whose metabolism is closely linked with that of folate and tetrahydrofolate.
See Also
External links
- Medical encyclopedia article on Tetrahydrofolate
- Wikipedia's article - Tetrahydrofolate
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