Tanomastat
Tanomastat (pronounced ta-NO-ma-stat) is a biomolecular compound that functions as a matrix metalloproteinase inhibitor (MMPI). It is primarily used in the field of oncology for its potential to inhibit the growth and spread of cancer cells.
Etymology
The term "Tanomastat" is derived from the Greek words "tano" meaning "stretch" and "mastat" meaning "to suppress". This is in reference to its function as a suppressor of cell growth and proliferation.
Function
Tanomastat is a non-peptidic biphenyl MMPI that specifically targets and inhibits the matrix metalloproteinases (MMPs). MMPs are a group of enzymes responsible for the degradation of extracellular matrix (ECM) components. By inhibiting these enzymes, Tanomastat prevents the breakdown of the ECM, thereby inhibiting the invasion and metastasis of cancer cells.
Clinical Use
Tanomastat has been studied in clinical trials for its potential use in the treatment of various types of cancer, including breast cancer, lung cancer, and colorectal cancer. However, as of now, it is not yet approved for clinical use.
Related Terms
- Matrix Metalloproteinase Inhibitor
- Biomolecular Compound
- Oncology
- Cancer
- Metastasis
- Extracellular Matrix
- Breast Cancer
- Lung Cancer
- Colorectal Cancer
External links
- Medical encyclopedia article on Tanomastat
- Wikipedia's article - Tanomastat
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