Syngeneic

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Syngeneic

Syngeneic (pronunciation: sin-juh-nee-ik) is a term used in transplantation and genetics to describe a particular type of genetic relationship between donor and recipient.

Etymology

The term "syngeneic" is derived from the Greek words "syn", meaning "together", and "genes", meaning "born". It is used to describe a situation where the donor and recipient are genetically identical.

Definition

In the context of transplantation, a syngeneic transplant refers to a procedure where the donor and the recipient are genetically identical. This typically occurs in the case of identical twins. Because the genetic makeup of the donor and recipient are the same, there is no risk of graft-versus-host disease (GVHD), a common complication of allogeneic transplants.

In genetics, syngeneic refers to a strain of organisms that are genetically identical or nearly so. This is often used in research to ensure that results are not skewed by genetic variability.

Related Terms

  • Allogeneic: Refers to a transplant where the donor and recipient are not genetically identical, typically a sibling or unrelated donor.
  • Autologous: Refers to a transplant where the donor and recipient are the same individual.
  • Graft-versus-host disease (GVHD): A complication of allogeneic transplants where the donor cells attack the recipient's body.
  • Transplantation: The process of transferring cells, tissues, or organs from one site to another.

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