Stromal cell
Stromal Cell
Stromal cell (/ˈstroʊməl/; from Ancient Greek: στρῶμα, romanized: strôma, meaning 'bed, mattress') is a type of cell found within various tissues. They provide structure and support to the other cells that make up the tissues and organs in which they are found.
Function
Stromal cells are primarily involved in the support of other cells, but they also have other functions. They can differentiate into other cell types, contribute to the immune response, and play a role in tissue repair and regeneration. They are also involved in the formation of blood vessels and the regulation of cell growth and differentiation.
Types
There are several types of stromal cells, including fibroblasts, endothelial cells, and pericytes. Each type has a specific role in the body and is found in different tissues and organs.
Fibroblasts
Fibroblasts are the most common type of stromal cell. They produce collagen and other extracellular matrix proteins that provide structure and support to tissues.
Endothelial Cells
Endothelial cells line the inside of blood vessels and play a crucial role in the regulation of blood flow and the delivery of oxygen and nutrients to tissues.
Pericytes
Pericytes are found on the outer surface of blood vessels and contribute to the stability and function of the vessels.
Clinical Significance
Stromal cells have been implicated in a number of diseases, including cancer, fibrosis, and inflammatory diseases. They can also be used in regenerative medicine due to their ability to differentiate into other cell types.
External links
- Medical encyclopedia article on Stromal cell
- Wikipedia's article - Stromal cell
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