Stratum granulosum
Stratum Granulosum
The Stratum Granulosum (pronounced: stra-tum gran-u-lo-sum) is a thin layer of the epidermis that lies between the stratum corneum and the stratum spinosum.
Etymology
The term 'Stratum Granulosum' is derived from Latin, where 'stratum' means 'layer' and 'granulosum' means 'granular'. This name is given due to the granular appearance of the cells in this layer.
Function
The primary function of the Stratum Granulosum is to aid in the skin's barrier function. It helps to prevent water loss and protects the body from harmful external substances. The cells in this layer produce a lipid-rich substance that contributes to the skin's waterproofing properties.
Structure
The Stratum Granulosum is composed of three to five layers of flattened, diamond-shaped keratinocytes. These cells contain keratohyalin granules and lamellar bodies, which contribute to the formation of the skin's barrier function.
Related Terms
- Epidermis: The outermost layer of the skin, which is composed of multiple sub-layers, including the Stratum Granulosum.
- Keratinocytes: The primary cell type found in the epidermis, which produce keratin, a protein that provides strength and durability to the skin.
- Stratum Corneum: The outermost sub-layer of the epidermis, which consists of dead skin cells that have migrated up from the Stratum Granulosum.
- Stratum Spinosum: The sub-layer of the epidermis that lies directly beneath the Stratum Granulosum. It is characterized by its spiny appearance due to the presence of desmosomes.
External links
- Medical encyclopedia article on Stratum granulosum
- Wikipedia's article - Stratum granulosum
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