Standardized Kt/V

From WikiMD.org
Jump to navigation Jump to search

Standardized Kt/V

Standardized Kt/V (pronounced as "kay tee over vee") is a dimensionless number used in medicine to quantify the adequacy of dialysis treatment in patients with kidney disease. The term is derived from three variables: K (dialyzer clearance of urea), t (dialysis time), and V (volume of distribution of urea, approximately equal to patient's total body water).

Etymology

The term "Standardized Kt/V" is a mathematical representation of the dialysis treatment adequacy. The 'K' stands for the dialyzer clearance rate, 't' for the duration of the dialysis treatment, and 'V' for the volume of distribution of urea in the body. The term was first introduced in the late 20th century as a measure to standardize the assessment of dialysis adequacy across different patients and treatment modalities.

Calculation

The calculation of Standardized Kt/V involves the use of a formula that takes into account the patient's pre- and post-dialysis urea concentrations, the dialyzer clearance rate, the duration of the dialysis session, and the patient's total body water volume. The formula is as follows:

Standardized Kt/V = -ln(R - 0.008*t) + (4 - 3.5*R) * UF/W

where:

  • R is the ratio of post-dialysis to pre-dialysis blood urea nitrogen concentration
  • t is the duration of the dialysis session (in hours)
  • UF is the ultrafiltration volume (in liters)
  • W is the post-dialysis weight (in kilograms)

Related Terms

  • Dialysis: A medical procedure that removes waste and excess fluid from the blood when the kidneys are not able to adequately do so.
  • Kidney Disease: A condition characterized by the gradual loss of kidney function over time.
  • Urea: A waste product formed in the liver, which is removed from the body by the kidneys.
  • Blood Urea Nitrogen (BUN): A medical test that measures the amount of urea nitrogen in the blood to assess kidney function.

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski