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- ...difficulty breathing, chest tightness, wheezing, coughing, and runny nose. Singulair blocks the effects of a substance that causes narrowing of the airways in t ...difficulty breathing, chest tightness, wheezing, coughing, and runny nose. Singulair blocks the effects of a substance that causes narrowing of the airways in t864 bytes (125 words) - 18:10, 13 January 2023