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...as '''4p- syndrome''', is a rare [[genetic disorder]] caused by a partial deletion of the short arm of [[chromosome 4]]. ...rn]] and [[Herbert L. Cooper]], who first identified it in 1961. The term "4p-" refers to the specific location of the genetic mutation on the fourth chr

...t (p) arm of chromosome 4. This chromosomal change is sometimes written as 4p-. ...cial appearance, as well as genetic testing to identify the characteristic deletion of genetic material on chromosome 4.