Sevelamer
Sevelamer
Sevelamer (pronounced: se-VEL-a-mer) is a phosphate binding drug used to prevent hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption. Sevelamer was approved by the U.S. Food and Drug Administration (FDA) in October 1998.
Etymology
The name "Sevelamer" is derived from its chemical structure. The "Se" is for poly(allylamine hydrochloride), the "vel" is for the crosslinking agent epichlorohydrin, and "amer" is a common suffix for polymers.
Usage
Sevelamer is used to control phosphorus levels in people with chronic kidney disease who are on dialysis. It is a type of drug known as a phosphate binder. Sevelamer helps to reduce the level of phosphate in the body by binding to it in the intestines and preventing it from being absorbed into the body.
Related Terms
- Hyperphosphatemia: A condition characterized by elevated levels of phosphate in the blood.
- Chronic kidney disease: A long-term condition where the kidneys do not work effectively.
- Dialysis: A procedure to remove waste products and excess fluid from the blood when the kidneys stop working properly.
- Phosphate binder: A medication used to reduce the absorption of phosphate from food in the digestive tract.
Side Effects
Common side effects of Sevelamer include nausea, vomiting, diarrhea, and stomach pain. If these effects persist or worsen, patients are advised to inform their doctor or pharmacist promptly.
Precautions
Before taking Sevelamer, patients should inform their doctor or pharmacist if they are allergic to it; or if they have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
External links
- Medical encyclopedia article on Sevelamer
- Wikipedia's article - Sevelamer
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