Senna

From WikiMD
Jump to navigation Jump to search

Senna is a plant used in traditional Chinese medicine and Ayurvedic medicine. The leaves are used to make a stimulant laxative that increases the frequency of bowel movements and relieves constipation. It is widely used in over-the-counter laxatives. Latin name: Senna alexandrina.

Information about Senna

Senna is a popular herbal laxative that is available without prescription. 

Liver safety of Senna

Senna is generally safe and well tolerated, but can cause adverse events including clinically apparent liver injury when used in high doses for longer than recommended periods.  

Mechanism of action of Senna

Senna belongs to a large genus of flowering plants found throughout the tropics, commonly used species being Cassia acutifolio (Alexandrian senna) and C. angustifolio (Indian or Tinnevelly senna).  Extracts of the leaves, flowers and fruit of senna have been used for centuries in folk medicine as a laxative and stimulant.  Senna is also included in several herbal teas, used for purging and in weight loss.  The active components in senna extracts are anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides.  They appear to act as a local irritant on the colon, which promotes peristalsis and evacuation.  Senna may also enhance intestinal fluid accumulation and increase the moisture content of stool by inhibiting electrolyte and water reabsorption from the colon.  Senna is minimally absorbed. 

Clinical use of Senna

Senna is used in many over-the-counter laxatives in combination with other agents under trade names such as Ex-lax, Fletcher’s Castoria and Senokot.  The typical dose is 15 to 30 mg of sennosides twice a day, but is recommended for short term use only (less than one week). 

Side effects of Senna

Side effects include abdominal cramps and electrolyte imbalance.  Long term use or abuse can lead to “cathartic” colon with diarrhea, cramps, weight loss and darkened pigmentation of the colonic mucosa.

Herbal and dietary supplements

Chinese and Other Asian Herbal Medicines

Multi-Ingredient Nutritional Supplements

See also Nutritional supplements

Cost and Coupons - Senna

Reviews for Senna


WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals.

Articles on Senna

This article is a stub. YOU can help Wikimd by expanding it!

Learn more about Senna

Drug classes

WikiMD Resources for Senna

Articles

Most recent articles

Most cited

Review articles

Articles on Senna in N Eng J Med, Lancet, BMJ

Media Senna

Powerpoint slides

Podcasts and MP3's

Videos

Evidence Based Medicine

Cochrane Collaboration

Clinical Trials

Ongoing Trials on Senna

Trial results on Senna

Clinical Trials on Senna at Google

Books and news

Books on Senna

Senna in the news

Commentary Senna

Blogs on Senna

Patient Resources / Community

Patient resources

Discussion groups

Patient Handouts

Other resources

Social Media

Reddit
Quora.png
Pins
Instagram
YouTube videos
Flickr
Bing.png

W8MD Weight Loss, Sleep & MedSpa

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U |V | W | X | Y | Z

Ad. Tired of being overweight? W8MD's insurance weight loss program can HELP* | Lose weight King of Prussia, PA | Lose weight NYC | Lose weight NJ | Lose weight Philadelphia Advertise

Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer. * Individual results may vary for weight loss from our sponsors.

Our sponsors WikiMD is supported by W8MD weight loss, sleep and medical aesthetic centers.