W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
29,027 pages, 4,107,492 edits & 35,725,970 views.

Free unbiased diet, health and wellness info!


From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

Information about Scopolamine

Propantheline is an anticholinergic agent used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.


Liver safety of Scopolamine

Propantheline has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.

Mechanism of action of Scopolamine

Propantheline (proe pan' the leen) is a synthetic quaternary ammonium anticholinergic agent which inhibits the muscarinic actions of acetylcholine on autonomic nerve endings, decreasing respiratory and gastrointestinal secretions and intestinal motility. Propantheline has broad activity against muscarinic acetylcholine receptors, but its highly polar quaternary ammonium group makes it less likely to cross lipid membranes such as the blood brain barrier, which is believed to decrease the potential for central nervous system effects. Propantheline has been used largely to alleviate symptoms of irritable bowel syndrome, painful gastrointestinal motility disorders and acid-peptic ulcer disease.

FDA approval information for Scopolamine

Propantheline was approved for use in the United States in 1953 but is now not commonly used, having been replaced by more effective antiulcer agents.

Dosage and administration for Scopolamine

Propantheline is available in tablets of 7.5 and 15 mg in generic forms and under the brand name Pro-Banthine. The typically recommended oral dose in adults is 7.5 to 15 mg three times daily and 30 mg at bedtime. Common side effects are those of parasympathetic stimulation and include dryness of the mouth and eyes, decreased sweating, headache, visual blurring, constipation, and urinary retention. Because of its structure, propantheline is believed to be less likely than other anticholinergics to cross the blood brain barrier and cause central nervous system effects such as restlessness, confusion and hallucinations. Anticholinergic agents can precipitate acute narrow angle glaucoma and acute urinary retention.

anticholinergic agents

Cost and Coupons - Scopolamine

Reviews for Scopolamine

Learn more about Scopolamine

Latest research (Pubmed)


External links


WikiMD needs you!

This WikiMD article Scopolamine is a stub.
If you are a healthcare professional familiar with the topic Scopolamine, or
A subject matter expert or authority on Scopolamine, you can help us.
About | Mission | Paid editors welcome!

Scopolamine is part of WikiMD's Physician reviewed^ articles available 4free, 4all, 4ever!
Medicine: Health - Encyclopedia‏‎‏‎ - Topics‏‎ -‏‎ Diseases‏‎ - Cancer - Rare diseases - Random Page Navigation: Drugs - Wellness - Obesity‏‎ - Diet - Ketogenic diet - W8MD weight loss diet - Editors: Recently Edited Pages - Alphabetical Order - Sponsors - USMLE The content on or accessible through WikiMD is for informational purposes only. WikiMD is not a substitute for professional medical advice. ^See full Disclaimers
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP*
Special: W8MD's tele-weight loss consultations only $99.99. Call 718-946-5500. Limited acceptance.