Sclerotome
Sclerotome
Sclerotome (pronounced: skle-ro-tome) is a term used in Embryology and Anatomy to describe a group of cells in a developing embryo that will eventually form the vertebrae and some other skeletal parts.
Etymology
The term 'Sclerotome' is derived from the Greek words 'skleros' meaning hard, and 'tome' meaning a cutting or section. This is in reference to the role these cells play in forming the 'hard' parts of the body, such as the vertebrae and ribs.
Development
In the early stages of embryonic development, the mesoderm differentiates into several layers. One of these layers forms a structure known as the somite. Each somite further differentiates into a dermomyotome and a sclerotome. The cells of the sclerotome migrate and surround the notochord and neural tube, eventually forming the vertebrae and ribs.
Related Terms
- Somite: A transient structure formed during the embryonic development of all bilaterians.
- Dermomyotome: A group of cells in a somite that will give rise to both dermis and muscle tissue.
- Mesoderm: One of the three primary germ layers in the very early embryo.
- Notochord: A flexible rod made out of a material similar to cartilage. If a species has a notochord at any stage of its life, it is, by definition, a member of the phylum Chordata.
- Neural tube: The embryonic precursor to the central nervous system, which is made up of the brain and spinal cord.
External links
- Medical encyclopedia article on Sclerotome
- Wikipedia's article - Sclerotome
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