Russell bodies
Russell Bodies
Russell bodies (pronounced: /ˈrʌsəl ˈbɒdiz/) are eosinophilic, large, homogeneous immunoglobulin-containing inclusions usually found in a plasma cell undergoing abnormal maturational changes. They were first described by a British pathologist, William Russell in 1890.
Etymology
The term "Russell bodies" is named after William Russell (1852–1940), a British pathologist who first described these inclusions in 1890.
Description
Russell bodies are typically found in conditions where there is long-standing antigenic stimulation, such as chronic infections or autoimmune diseases. They are also seen in certain types of cancer, such as multiple myeloma. These bodies are essentially packed with immunoglobulins, which are proteins that the body produces in response to foreign substances.
Related Terms
- Plasma cell: A type of white blood cell that produces a specific type of antibody.
- Immunoglobulin: A protein produced by plasma cells and lymphocytes and characteristic of these types of cells.
- Antigen: A substance that induces a specific immune response and can stimulate the production of antibodies when introduced into the body.
- Autoimmune disease: A condition in which your immune system mistakenly attacks your body.
- Multiple Myeloma: A cancer of plasma cells.
See Also
External links
- Medical encyclopedia article on Russell bodies
- Wikipedia's article - Russell bodies
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