Rucaparib

From WikiMD.org
Jump to navigation Jump to search

Rucaparib

Rucaparib (pronounced roo-KAP-a-rib) is a pharmaceutical drug used in the treatment of certain types of cancer, specifically ovarian cancer and prostate cancer. It is a type of PARP inhibitor, which works by preventing cancer cells from repairing their own DNA, leading to cell death.

Etymology

The name "Rucaparib" is derived from the chemical structure of the drug, which is a member of the class of drugs known as poly(ADP-ribose) polymerase (PARP) inhibitors. The "ru" comes from the first two letters of "rubidium", a chemical element used in the synthesis of the drug, and "caparib" is a common suffix used for drugs in this class.

Usage

Rucaparib is used in the treatment of advanced ovarian cancer that has been treated with two or more chemotherapies and continues to progress. It is also used in the treatment of metastatic castration-resistant prostate cancer with a specific genetic mutation.

Related Terms

  • Chemotherapy: A type of cancer treatment that uses drugs to kill cancer cells.
  • Ovarian Cancer: A type of cancer that begins in the ovaries.
  • Prostate Cancer: A type of cancer that occurs in the prostate, a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm.
  • PARP inhibitor: A type of drug that blocks an enzyme called poly (ADP-ribose) polymerase (PARP). PARP helps repair DNA when it becomes damaged.

Side Effects

Common side effects of Rucaparib include fatigue, nausea, vomiting, anemia, abdominal pain, and increased liver enzymes. More serious side effects can include myelodysplastic syndrome, acute myeloid leukemia, and pneumonitis.

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski