Rovelizumab

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Rovelizumab

Rovelizumab (pronunciation: roh-veh-LIZ-uh-mab) is a monoclonal antibody that was developed for the treatment of acute stroke. It was designed to target and neutralize the interleukin-1 beta (IL-1β), a pro-inflammatory cytokine that plays a key role in the pathogenesis of acute stroke.

Etymology

The name "Rovelizumab" is derived from the standard nomenclature for monoclonal antibodies. The suffix "-mab" indicates that it is a monoclonal antibody, while the prefix "Rove-" does not have a specific meaning and is used to create a unique name.

Mechanism of Action

Rovelizumab works by binding to the IL-1β, thereby preventing it from interacting with its receptor and triggering the inflammatory response that contributes to the damage caused by acute stroke.

Related Terms

  • Monoclonal antibody: A type of protein made in the laboratory that can bind to substances in the body, including cancer cells.
  • Interleukin-1 beta: A pro-inflammatory cytokine that is produced by activated macrophages and plays a key role in the inflammatory response.
  • Acute stroke: A medical condition in which poor blood flow to the brain results in cell death.

See Also

External links

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