Rocuronium

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Rocuronium

Rocuronium (pronounced roh-koo-ROH-nee-uhm) is a type of non-depolarizing muscle relaxant used in modern anesthesia. It is often used to facilitate endotracheal intubation and to provide muscle relaxation during surgery or mechanical ventilation.

Etymology

The term "rocuronium" is derived from the Latin rocurare, meaning "to relax", and the Greek onium, a suffix often used in the names of drugs.

Pharmacology

Rocuronium acts by competitively binding to nicotinic acetylcholine receptors on the motor end-plate. This binding results in a block of the ion channel, preventing the flow of ions and leading to muscle relaxation.

Clinical Use

Rocuronium is used in a clinical setting to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is also used to facilitate endotracheal intubation, a procedure in which a tube is inserted into the trachea to maintain an open airway.

Side Effects

Possible side effects of rocuronium include hypotension, tachycardia, and bronchospasm. In rare cases, it can cause anaphylaxis, a severe allergic reaction.

Related Terms

External links

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