Resistin
Resistin
Resistin (pronounced reh-sis-tin), also known as Adipose Tissue-Specific Secretory Factor (ADSF) or Found in Inflammatory Zone 3 (FIZZ3), is a hormone secreted by adipose tissue. The term "Resistin" is derived from the word "resistance" and the suffix "-in", indicating its initial discovery as a factor that contributes to insulin resistance.
Pronunciation
Resistin is pronounced as /rɛˈsɪstɪn/.
Etymology
The term "Resistin" is a combination of the English word "resist" and the common protein suffix "-in". It was named for its role in inducing insulin resistance.
Function
Resistin is a cysteine-rich protein that in humans is encoded by the RETN gene. It is produced by adipocytes and is known to increase during obesity and may contribute to insulin resistance. Resistin interferes with the ability of insulin to suppress glucose production by the liver and therefore could play a role in the development of type 2 diabetes.
Related Terms
- Adipocyte: A type of cell that stores fat, producing resistin among other hormones.
- Insulin resistance: A condition in which cells fail to respond normally to the hormone insulin, to which resistin contributes.
- Type 2 diabetes: A chronic condition that affects the way the body processes blood sugar (glucose), potentially influenced by resistin levels.
- Cysteine-rich protein: A type of protein that contains a high proportion of cysteine amino acids, such as resistin.
External links
- Medical encyclopedia article on Resistin
- Wikipedia's article - Resistin
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