Relapsing-remitting MS
Relapsing-remitting MS
Relapsing-remitting MS (pronunciation: re-laps-ing re-mit-ing em-es), often abbreviated as RRMS, is the most common disease course of Multiple Sclerosis. It is characterized by clearly defined attacks of new or increasing neurologic symptoms, followed by periods of partial or complete recovery (remissions).
Etymology
The term "Relapsing-remitting" refers to the pattern of symptoms in this form of MS. "Relapsing" means to fall back or deteriorate, which in this context refers to the return or worsening of neurological symptoms. "Remitting" means to diminish or lessen, referring to the periods of recovery or remission that follow relapses.
Symptoms
Symptoms of RRMS can vary widely and may include fatigue, difficulty walking, numbness or tingling, muscle spasms, stiffness and weakness, problems with coordination and balance, and problems with thinking and memory. These symptoms are caused by inflammation and damage to the myelin sheath, the protective covering of nerve fibers in the central nervous system, which disrupts the normal flow of electrical impulses along the nerves.
Treatment
While there is currently no cure for RRMS, there are several disease-modifying therapies (DMTs) available that can help to reduce the frequency and severity of relapses and slow the progression of disability. These include interferon beta-1a, interferon beta-1b, glatiramer acetate, teriflunomide, dimethyl fumarate, and fingolimod.
Prognosis
The course of RRMS can be unpredictable. Some people may experience only a few mild symptoms, while others may develop significant disability. The disease tends to have a better prognosis than other forms of MS, with longer periods of remission and a slower progression of disability.
See also
External links
- Medical encyclopedia article on Relapsing-remitting MS
- Wikipedia's article - Relapsing-remitting MS
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