Quantitative trait locus
Quantitative Trait Locus (QTL)
Quantitative Trait Locus (pronunciation: kwon-ti-tey-tiv treyt loh-kuhs, plural: Quantitative Trait Loci) is a region of DNA that correlates with variation in a phenotype. The QTL contains and is named after the gene(s) that control that phenotype.
Etymology
The term "Quantitative Trait Locus" originates from the field of genetics. "Quantitative" refers to a trait that can be measured numerically and shows continuous variation, as opposed to a qualitative trait which is characterized by discrete categories. "Trait" refers to a characteristic or attribute of an organism that can be observed or measured. "Locus" is a term used in genetics to refer to a specific location on a chromosome.
Related Terms
- Genetic Linkage: The tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.
- Genome-Wide Association Study (GWAS): An observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a trait.
- Marker Assisted Selection (MAS): A process used in plant and animal breeding in which the selection of individuals to be crossed is based on known genotypes at marker loci.
- Polygenic Trait: A trait that is controlled by a group of non-allelic genes.
- Single Nucleotide Polymorphism (SNP): A substitution of a single nucleotide that occurs at a specific position in the genome.
See Also
External links
- Medical encyclopedia article on Quantitative trait locus
- Wikipedia's article - Quantitative trait locus
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