Pyoderma gangrenosum
Pyoderma gangrenosum (pronunciation: py-o-der-ma gang-re-no-sum) is a rare, non-infectious skin condition that causes large, painful ulcers. It's often associated with other diseases, most commonly inflammatory bowel disease, arthritis, and certain blood disorders.
Etymology
The term "Pyoderma gangrenosum" is derived from the Greek words "pyon" meaning pus, "derma" meaning skin, and "gangraina" meaning decay of tissues.
Symptoms
The initial symptoms of Pyoderma gangrenosum often include small, tender bumps (papules) or blisters (pustules) on the skin. These can rapidly progress to painful, open sores that may be deep and large. The ulcers usually appear on the legs but can occur anywhere on the skin.
Causes
The exact cause of Pyoderma gangrenosum is unknown. However, it's often associated with certain health problems, such as Ulcerative colitis, Crohn's disease, Rheumatoid arthritis, and Myeloma. It's thought that the condition may be caused by an abnormal response of the immune system.
Diagnosis
Diagnosis of Pyoderma gangrenosum is typically based on the appearance of the skin ulcers and a patient's medical history. There's no specific test for the condition, but tests may be done to rule out other conditions that can cause similar symptoms.
Treatment
Treatment for Pyoderma gangrenosum usually involves medications to help reduce inflammation and heal the ulcers. This may include corticosteroids, immunosuppressants, and biologic therapies. In some cases, surgery may be needed to remove dead tissue from the ulcers.
See also
External links
- Medical encyclopedia article on Pyoderma gangrenosum
- Wikipedia's article - Pyoderma gangrenosum
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