Progressive massive fibrosis

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Progressive Massive Fibrosis

Progressive Massive Fibrosis (PMF) (pronounced: pro-gres-iv mas-iv fai-bro-sis) is a severe form of pneumoconiosis characterized by the presence of large masses of fibrotic tissue in the lungs.

Etymology

The term "Progressive Massive Fibrosis" is derived from the progressive nature of the disease, the massive fibrotic masses that form in the lungs, and the term "fibrosis" which refers to the formation of excess fibrous connective tissue in an organ.

Definition

Progressive Massive Fibrosis is a condition that results from the accumulation of dust in the lungs over a prolonged period, leading to inflammation and eventually fibrosis. This condition is most commonly associated with coal workers' pneumoconiosis, but can also occur as a result of other types of pneumoconiosis such as silicosis and asbestosis.

Symptoms

Symptoms of Progressive Massive Fibrosis may include shortness of breath, cough, chest pain, and fatigue. As the disease progresses, it can lead to respiratory failure and other serious complications.

Diagnosis

Diagnosis of Progressive Massive Fibrosis typically involves a combination of medical history, physical examination, and imaging tests such as chest X-ray or CT scan. Lung function tests may also be used to assess the severity of the disease.

Treatment

Treatment for Progressive Massive Fibrosis primarily involves managing symptoms and preventing further exposure to dust. This may include medications to relieve symptoms, oxygen therapy for those with severe disease, and lifestyle changes such as quitting smoking and avoiding exposure to dust.

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