Progressive supranuclear palsy

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Progressive Supranuclear Palsy (PSP) (pronunciation: /prəˈɡresiv ˌsuːprəˈnjuːklɪər ˈpɑːlzɪ/), also known as Steele-Richardson-Olszewski syndrome, is a rare neurodegenerative disease that involves the gradual deterioration and death of specific volumes of the brain.

Etymology

The term "Progressive Supranuclear Palsy" is derived from the nature of the disease itself. "Progressive" refers to the continually worsening nature of the disease, "Supranuclear" refers to the areas of the brain affected (above the nucleus), and "Palsy" refers to the weakness or problems with movement typical of this condition.

Symptoms

The symptoms of PSP include problems with balance and movement, changes in behavior, mood, and personality, and difficulties with vision. These symptoms are due to the gradual deterioration of brain cells in specific parts of the brain.

Causes

The exact cause of PSP is unknown, but it is believed to be related to a buildup of a protein called tau in the brain. This buildup leads to the damage and death of brain cells.

Diagnosis

Diagnosis of PSP is based on the presence of characteristic symptoms and findings on neurological examination. There is no specific test for PSP, and the diagnosis can be difficult because the symptoms can be similar to those of other neurological conditions.

Treatment

There is currently no cure for PSP, but there are treatments available to help manage the symptoms. These include medications to manage movement problems and physical therapy to help with balance and mobility.

Related Terms

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