Primosome
Primosome
Primosome (pronunciation: /ˈprɪməˌsoʊm/) is a protein complex that is involved in the initiation of DNA replication. The term is derived from the Latin primus, meaning "first", and the Greek soma, meaning "body".
Etymology
The term "primosome" is derived from the Latin word primus, meaning "first", and the Greek word soma, meaning "body". This is in reference to the primosome's role in initiating the first step of DNA replication.
Function
The primosome plays a crucial role in the initiation of DNA replication. It is responsible for creating a primer, which is a short nucleic acid sequence that provides a starting point for DNA synthesis. The primosome is composed of several proteins, including the primase enzyme, which synthesizes the primer, and helicase, which unwinds the DNA double helix.
Related Terms
- DNA replication: The process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules.
- Primase: An enzyme that synthesizes a short RNA sequence (the primer) that is complementary to the DNA template strand.
- Helicase: An enzyme that unwinds the DNA double helix during DNA replication.
- Replication fork: The area where the DNA double helix is separated into two single strands that serve as templates for replication.
See Also
External links
- Medical encyclopedia article on Primosome
- Wikipedia's article - Primosome
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