Platelet-rich fibrin

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Platelet-rich fibrin

Platelet-rich fibrin (PRF) (pronunciation: /ˈpleɪtlɪt rɪʧ ˈfaɪbrɪn/) is a second-generation platelet concentration system that is used in various medical fields, including dentistry, orthopedics, and plastic surgery. It is a natural fibrin-based biomaterial prepared from an individual's own blood.

Etymology

The term "platelet-rich fibrin" is derived from its composition. "Platelet-rich" refers to the high concentration of platelets in the material, while "fibrin" refers to the fibrin matrix that holds the platelets together.

Preparation

PRF is prepared by drawing a patient's blood and centrifuging it without an anticoagulant. This process separates the blood into three layers: a top layer of plasma, a middle layer of PRF, and a bottom layer of red blood cells.

Uses

PRF is used in various medical procedures to promote healing and tissue regeneration. It is often used in combination with other treatments, such as bone grafting in dentistry or joint replacement surgery in orthopedics.

Related Terms

  • Platelet-rich plasma: A similar biomaterial that is also derived from a patient's own blood, but is prepared differently and has a different composition.
  • Fibrin glue: A type of surgical adhesive that is made from fibrin and other components of blood.
  • Autologous blood donation: The process of donating one's own blood for later use, such as in a surgical procedure.

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